CAJ | 학술논문

目的构建Lenke 1 BN型青少年特发性脊柱侧凸(adolescent idiopathic scoliosis,AIS)三维有限元模型,并验证其有效性,为AIS生物力学仿真研究建立理想的数字化平台.方法选择1例18岁女性Lenke 1 BN型AIS志愿者作为研究对象.取仰卧位,应用螺旋CT从T1椎体上缘至尾骨以1 mm间距进行连续扫描,获得Dicom格式CT图像539张.将CT图像导入逆向工程软件Mimics 10.01,建立包括胸-腰-骶尾椎和胸廓等结构的完整AIS三维几何模型.对模型进行几何清理,然后导入有限元前处理软件Hyper Mesh 7.0划分有限元实体单元,并参照文献添加椎间盘及韧带结构单元,生成完整的AIS三维有限元模型.参照文献赋予模型材料参数和实常数,并通过左、右Bending试验和仰卧-站立试验,对模型进行整体的有效性验证.结果成功构建了完整的Lenke 1 BN型AIS三维非线性有限元模型,共划分节点341 228个,四面体单元1 409 929个,壳单元163 132个,线缆单元715个和杆单元149个.有限元模拟左、右Bending试验和仰卧-站立试验误差分别为8.3%和3.9%.结论所建立的Lenke 1 BN型AIS三维有限元模型完整、逼真、可靠且有效,可用于进一步的AIS生物力学仿真研究.
목적 구건Lenke 1 BN형청소년특발성척주측철(adolescent idiopathic scoliosis,AIS)삼유유한원모형,병험증기유효성,위AIS생물역학방진연구건립이상적수자화평태.방법 선택1례18세녀성Lenke 1 BN형AIS지원자작위연구대상.취앙와위,응용라선CT종T1추체상연지미골이1 mm간거진행련속소묘,획득Dicom격식CT도상539장.장CT도상도입역향공정연건Mimics 10.01,건립포괄흉-요-저미추화흉곽등결구적완정AIS삼유궤하모형.대모형진행궤하청리,연후도입유한원전처리연건Hyper Mesh 7.0화분유한원실체단원,병삼조문헌첨가추간반급인대결구단원,생성완정적AIS삼유유한원모형.삼조문헌부여모형재료삼수화실상수,병통과좌、우Bending시험화앙와-참립시험,대모형진행정체적유효성험증.결과 성공구건료완정적Lenke 1 BN형AIS삼유비선성유한원모형,공화분절점341 228개,사면체단원1 409 929개,각단원163 132개,선람단원715개화간단원149개.유한원모의좌、우Bending시험화앙와-참립시험오차분별위8.3%화3.9%.결론 소건립적Lenke 1 BN형AIS삼유유한원모형완정、핍진、가고차유효,가용우진일보적AIS생물역학방진연구.
Objective To set up and validate three-dimensional finite element model (FEM) of Lenke 1 BN idiopathic scoliosis based on CT images, for building ideal digitization platform for further biomechanical study. Methods An 18-year-old female Lenke 1 BN idiopathic scoliosis patient was selected as volunteer for current study. CT transverse scanning in supine position was done from T1 to caudal end in 1mm layer interval. All CT images were imported into Mimics 10.01 to form qualified AIS three-dimensional geometric model after geometry clean, including all thoraco-lumbar-sacral vertebrae and thoracic cage, which was further delivered to Hypher Mesh 7.0 to build 3d finite element AIS model by mesh partition and quality control. A variety of material parameters were given to different mesh according to references. Validation verification was done by left and right Bending test and erect-supine test. Results 1 )A complete three-dimensional finite element model of Lenke 1 BN idiopathic scoliosis was built successfully, in consist of 341 228 nodes,1 409 929 tetrahedron elements, 163 132 shell elements, 715 cable elements and 149 rod elements. 2)The convex bending Cobb's angles of PT, MT and L curve on X-ray films and finite element simulation were 14°,26° ,8° and 15° ,24°,6° respectively. The error of finite element simulation was 8.3%. 3)Erect Cobb's angles of PT, MT and L were 37°, 50°, 24° and 33°, 51°, 24° on X-ray films and by finite element simulation.Supine Cobb's angles of PT, MT and L were 29°, 43°, 22° and 27°, 42°, 22° on X-ray films and by finite element simulation. The average error of finite element simulation was 3.9%. Conclusion Lenke 1 BN idiopathic scoliosis FEM is intact, reliable and effective for further biomechanical simulation study.