CAJ | 학술논문

目的探讨颅脑静脉窦内血栓磁共振弥散加权成像(DWl)的特征以及DWI表现与溶栓治疗后血管再通的关系.方法回顾性分析14例颅脑静脉窦内血栓患者的MRI表现,包括常规MRJ、FLAIR、DWI及MRV,统计静脉窦内出现DWI高信号的部位、数量;以溶栓治疗后1～3个月的MRV确定原栓塞静脉窦是否再通;探讨溶栓前静脉窦内血栓T1WI、FLAIR、DWI表现与溶栓治疗后血管再通的关系.结果 14例颅脑静脉窦内血栓患者中9例出现21个部位的血栓DWI高信号.首诊MRI血栓内有DWI高信号的静脉窦的血管完全再通的几率较低(19.0%),血栓内无DWI高信号的静脉窦冉通率较高(68.2%),比较差异有统计学意义(P=0.005).结论颅脑静脉窦内血栓患者血栓DWI信号可能与血栓的进展有关,首诊MRI发现静脉窦内血栓DWI呈高信号能预测溶栓治疗1～3个月后血管再通率较低.
목적 탐토로뇌정맥두내혈전자공진미산가권성상(DWl)적특정이급DWI표현여용전치료후혈관재통적관계.방법 회고성분석14례로뇌정맥두내혈전환자적MRI표현,포괄상규MRJ、FLAIR、DWI급MRV,통계정맥두내출현DWI고신호적부위、수량;이용전치료후1～3개월적MRV학정원전새정맥두시부재통;탐토용전전정맥두내혈전T1WI、FLAIR、DWI표현여용전치료후혈관재통적관계.결과 14례로뇌정맥두내혈전환자중9례출현21개부위적혈전DWI고신호.수진MRI혈전내유DWI고신호적정맥두적혈관완전재통적궤솔교저(19.0%),혈전내무DWI고신호적정맥두염통솔교고(68.2%),비교차이유통계학의의(P=0.005).결론 로뇌정맥두내혈전환자혈전DWI신호가능여혈전적진전유관,수진MRI발현정맥두내혈전DWI정고신호능예측용전치료1～3개월후혈관재통솔교저.
Objective To investigate diffusion-weighted(DWI)magnetic resonance imaging (MRI) features of the thrombi in patients with cerebral sinus thrombosis(CST),and explore their relation with the recanalization rate alter thrombolytic therapy. Methods The clinical and imaging data were retrospectively analyzed in 14 CST cases,including conventional MRI,FLAIR,DWI and MRV features.The hyperintense signals on DWI at the site ofvenous occlusion were analyzed,and MRV was performed 1-3 months after the thrombolytic therapy to assess the recanalization.The relation between the findings by T1WI,FLAIR and DWI before the thrombolytic therapy and the recanalization rate after the therapy was evaluated.Results Hyperintense signals Was detected in 21 occluded sinuses in 9 patients(41%)with a recellt CVT.Hyperintense signals in the thrombi on the initial MRl were associated with a significantly lowered rate of complete recanalization of the vessel as compared with that among cases without the hyperintense signals(19.0%vs 68.2%,P=0.005). Conclusion The DWI signals of the thrombi in the cerebral venous sinuses can be associated with the progression of the thrombosis,and the presence of hyperintense signals in the occluded cerebral sinuses on the initial DWI may suggest a low rate of sinus recanalization after 1 t0 3 months of thrombolytic therapy.