CAJ | 학술논문

[目的]探讨阻塞性睡眠呼吸暂停( OSA)患者体重指数和年龄与呼吸暂停低通气指数(AHI)的相关性.方法对2985例经睡眠多导图(PSG)检查确诊为OSA的患者的体重指数和年龄与呼吸暂停低通气指数进行相关性分析.根据患者年龄分为青年组(18 -44岁)、中年组(45～59岁)和老年组(60～80岁),根据患者体重指数分为正常体重组( 18.5 ～ 23)、超重组(24～27)和肥胖组(＞28),比较不同年龄组和不同体重指数组OSA患者PSG的结果.结果 OSA患者AHI与体重指数呈正相关(r=0.445,P＜0.001),与患者年龄呈负相关(ι=-0.105,P＜0.05).肥胖组AHI[( 51.8±27.0)次/h]明显大于超重组[( 37.6±23.5)次/h]和正常组[( 27.5±21.5次/h)],三组之间的比较差异有统计学意义(P＜0.05).老年组AHI[( 37.7±23.3)次/h]明显小于中年组[( 41.1±25.2)次/h]和青年组[( 45.0±28.6)次/h],不同组之间的比较差异有统计学意义(P＜0.05).结论OSA患者AHI与BMI呈正相关,肥胖是OSA重要危险因素.
[목적]탐토조새성수면호흡잠정( OSA)환자체중지수화년령여호흡잠정저통기지수(AHI)적상관성.방법 대2985례경수면다도도(PSG)검사학진위OSA적환자적체중지수화년령여호흡잠정저통기지수진행상관성분석.근거환자년령분위청년조(18 -44세)、중년조(45～59세)화노년조(60～80세),근거환자체중지수분위정상체중조( 18.5 ～ 23)、초중조(24～27)화비반조(＞28),비교불동년령조화불동체중지수조OSA환자PSG적결과.결과 OSA환자AHI여체중지수정정상관(r=0.445,P＜0.001),여환자년령정부상관(ι=-0.105,P＜0.05).비반조AHI[( 51.8±27.0)차/h]명현대우초중조[( 37.6±23.5)차/h]화정상조[( 27.5±21.5차/h)],삼조지간적비교차이유통계학의의(P＜0.05).노년조AHI[( 37.7±23.3)차/h]명현소우중년조[( 41.1±25.2)차/h]화청년조[( 45.0±28.6)차/h],불동조지간적비교차이유통계학의의(P＜0.05).결론OSA환자AHI여BMI정정상관,비반시OSA중요위험인소.
Objective To explore the association of body mass index ( BMI ) and age with apnea-hypopnea index ( AHI ) in patients with obstructive sleep apnea ( OSA ).Methods Retrospectively studied 2985 patients with OSA comfirmed by polysomnograhy during the period of 2001 to 2011.The patients were dividing into young adult group ( aged 18 to 44 ),middle-age group( aged 45 to 59 ),and elderly group ( aged 60 to 80 ) basing on their age,and divided into normal weight group ( 18.5 - 23 ),overweight group ( 24 - 27 ),and obesity group ( ＞ 28 ) basing on their BMI.The relationship of AHI with BMI and age was analyzed.Results AHI was positively correlated with BMI ( r=0.445,P＜ 0.001 ) and age was negatively correlated with AHI ( r=-0.105,P＜ 0.05 ).AHI was significantly greater in the obesity group ( 51.8 ± 27.0 / h ) than in the overweight group ( 37.6 ± 23.5 / h ) and normal group ( 27.5 ± 21.5 / h );the difference was statistically significant among these three groups( P＜ 0.05 ).AHI was significantly less in the elderly group ( 37.7 ± 23.3 / h ) than in the middle-age group ( 41.1 ± 25.2 / h ) and youth adult group ( 45.0 ± 28.6 / h ); the difference was statistically significant among these groups ( P ＜ 0.05 ).Conclusions Apnea-hypopnea index is positively associated with body mass index in patients with obstructive sleep apnea.Obesity is an important risk factor for obstructive sleep apnea.