中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
7期
999-1000
,共2页
麻醉恢复期%地佐辛%芬太尼%苏芬太尼
痳醉恢複期%地佐辛%芬太尼%囌芬太尼
마취회복기%지좌신%분태니%소분태니
Anesthesia recovery period%Dezocine%Fentanyl%Remifentanil
目的 观察地佐辛诱导预防苏芬太尼麻醉苏醒期患者躁动的作用.方法 选择60例ASA Ⅰ～Ⅱ级上腹部手术患者,随机分为3组,每组均为20例,麻醉诱导均用咪哒唑仑0.05 mg/kg,异丙酚1～2mg/kg,维库溴铵0.12 mg/kg.镇痛药3组分别为:苏芬太尼组1μg/kg,芬太尼组4μg/kg,地佐辛组0.2 mg/kg.维持麻醉均用苏芬太尼、异丙酚.记录麻醉苏醒期3组患者镇痛评分( VAS)、躁动评分(RS),拔管时间和不良反应.结果 与苏芬太尼对比,芬太尼组、地佐辛组在麻醉苏醒期间,患者的血流动力学更平稳,与芬太尼组对比地佐辛组在麻醉苏醒期间Ramsay评分、VAS评分、RS评分更低,更安静(躁动减少)、呼吸抑制、呕吐、皮肤瘙痒等不良反应少(P＜0.05),拔管时间差异有统计学意义(P＜0.05).结论 0.2 mg/kg地佐辛用于全麻诱导麻醉苏醒期较芬太尼减少患者躁动,呼吸抑制、呕吐等不良反应发生率降低.
目的 觀察地佐辛誘導預防囌芬太尼痳醉囌醒期患者躁動的作用.方法 選擇60例ASA Ⅰ～Ⅱ級上腹部手術患者,隨機分為3組,每組均為20例,痳醉誘導均用咪噠唑崙0.05 mg/kg,異丙酚1～2mg/kg,維庫溴銨0.12 mg/kg.鎮痛藥3組分彆為:囌芬太尼組1μg/kg,芬太尼組4μg/kg,地佐辛組0.2 mg/kg.維持痳醉均用囌芬太尼、異丙酚.記錄痳醉囌醒期3組患者鎮痛評分( VAS)、躁動評分(RS),拔管時間和不良反應.結果 與囌芬太尼對比,芬太尼組、地佐辛組在痳醉囌醒期間,患者的血流動力學更平穩,與芬太尼組對比地佐辛組在痳醉囌醒期間Ramsay評分、VAS評分、RS評分更低,更安靜(躁動減少)、呼吸抑製、嘔吐、皮膚瘙癢等不良反應少(P＜0.05),拔管時間差異有統計學意義(P＜0.05).結論 0.2 mg/kg地佐辛用于全痳誘導痳醉囌醒期較芬太尼減少患者躁動,呼吸抑製、嘔吐等不良反應髮生率降低.
목적 관찰지좌신유도예방소분태니마취소성기환자조동적작용.방법 선택60례ASA Ⅰ～Ⅱ급상복부수술환자,수궤분위3조,매조균위20례,마취유도균용미달서륜0.05 mg/kg,이병분1～2mg/kg,유고추안0.12 mg/kg.진통약3조분별위:소분태니조1μg/kg,분태니조4μg/kg,지좌신조0.2 mg/kg.유지마취균용소분태니、이병분.기록마취소성기3조환자진통평분( VAS)、조동평분(RS),발관시간화불량반응.결과 여소분태니대비,분태니조、지좌신조재마취소성기간,환자적혈류동역학경평은,여분태니조대비지좌신조재마취소성기간Ramsay평분、VAS평분、RS평분경저,경안정(조동감소)、호흡억제、구토、피부소양등불량반응소(P＜0.05),발관시간차이유통계학의의(P＜0.05).결론 0.2 mg/kg지좌신용우전마유도마취소성기교분태니감소환자조동,호흡억제、구토등불량반응발생솔강저.
Objective To investigate the effects of induction with Dezocine to prevent the agitation of the patient after remifentanil anesthesia.Methods 60 patients of upper abdominal surgery,ASA Ⅰ ～ Ⅱ class,were randomly divided into 3 groups,20 patients in each group,anesthesia was induced with the midazolam 0.05 mg/kg,propofol 1 ～2mg/kg,vecuronium 0.12mg/kg.Analgesic drugs were administer as follow:control group,remifentanil ( group Rmf )1 μg/kg; fentanyl group ( group F) 4 μg/kg; Dezocine group ( group D) 0.2mg/kg.Remifentanil、propofol are used to maintain anesthesia.The time of recovery and extubation,the VAS pain score,the Ramsay score and adverse reactions such as vomiting,respiratory depression after extubation were recorded.Results Compared with group Rmf,the hemodynamic parameters was more stable in group F and group D.Compared with group F ( 1 μg/kg),the VAS pain score,the Ramsay score and adverse reactions significantly decreased in group D ( P ＜ 0.05 ),and the time of extubation in group F was longer than group D(P ＜ 0.05).Conclusion 0.2mg/kg of Dezocine could be used for the induction of anesthesia to reduce the incidence of agitation and adverse reactions during recovery period.
