CAJ | 학술논문

目的:探讨哺乳期内2,3,7,8-TCDD暴露对牙齿釉质的矿物质含量和晶体特性的影响.方法:分别从2,3,7,8-TCDD暴露组和对照组PD60仔鼠的牙齿釉质提取样品.应用组织灰化法测定矿物质含量.应用红外光谱技术评价晶体性质.结果:2,3,7,8-TCDD暴露组牙齿釉质矿物质含量同对照组相比出现降低情况,2组间比较,差异明显(分泌-早期成熟期釉质:57.8±8.9 Vs 42.2±10.8,P＜0.01；成熟期釉质:90.3±15.2 Vs 75.4±18.5,P＜0.05).所有釉质样品中均出现CO32-和PO43-特征性吸收峰,2,3,7,8-TCDD暴露组CO32-吸收峰吸光度较对照组高.红外吸收峰的峰形显示及定量测定显示,对照组釉质的CO32-:PO43-吸光度比较2,3,7,8-TCDD暴露组降低(分泌-早期成熟期釉质:0.4170±0.0324 Vs 0.4726±0.0533,P＜0.01；成熟期釉质:0.3356±0.0427 Vs 0.3944±0.0538,P＜0.01).结论:2,3,7,8-TCDD暴露使牙齿釉质的矿物质含量降低,牙齿釉质晶体结构出现改变.
목적:탐토포유기내2,3,7,8-TCDD폭로대아치유질적광물질함량화정체특성적영향.방법:분별종2,3,7,8-TCDD폭로조화대조조PD60자서적아치유질제취양품.응용조직회화법측정광물질함량.응용홍외광보기술평개정체성질.결과:2,3,7,8-TCDD폭로조아치유질광물질함량동대조조상비출현강저정황,2조간비교,차이명현(분비-조기성숙기유질:57.8±8.9 Vs 42.2±10.8,P＜0.01；성숙기유질:90.3±15.2 Vs 75.4±18.5,P＜0.05).소유유질양품중균출현CO32-화PO43-특정성흡수봉,2,3,7,8-TCDD폭로조CO32-흡수봉흡광도교대조조고.홍외흡수봉적봉형현시급정량측정현시,대조조유질적CO32-:PO43-흡광도비교2,3,7,8-TCDD폭로조강저(분비-조기성숙기유질:0.4170±0.0324 Vs 0.4726±0.0533,P＜0.01；성숙기유질:0.3356±0.0427 Vs 0.3944±0.0538,P＜0.01).결론:2,3,7,8-TCDD폭로사아치유질적광물질함량강저,아치유질정체결구출현개변.