中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2012年
3期
219-220
,共2页
王丽莉%诸葛欣%陈翊玲%张蕴
王麗莉%諸葛訢%陳翊玲%張蘊
왕려리%제갈흔%진익령%장온
糖尿病,2型%血管新生%人CXC趋化因子配体16
糖尿病,2型%血管新生%人CXC趨化因子配體16
당뇨병,2형%혈관신생%인CXC추화인자배체16
Diabetes mellitus,type 2%Angiogenesis%Human CXC-chemokine ligand 16
测定80例2型糖尿病患者和40名对照组人CXC趋化因子配体16、碱性成纤维细胞生长因子、血小板源性内皮细胞生长因子水平和内皮祖细胞数量,结果显示2型糖尿病患者存在血管新生障碍,高龄、HbA1c升高者及合并血管病变患者更为明显.
測定80例2型糖尿病患者和40名對照組人CXC趨化因子配體16、堿性成纖維細胞生長因子、血小闆源性內皮細胞生長因子水平和內皮祖細胞數量,結果顯示2型糖尿病患者存在血管新生障礙,高齡、HbA1c升高者及閤併血管病變患者更為明顯.
측정80례2형당뇨병환자화40명대조조인CXC추화인자배체16、감성성섬유세포생장인자、혈소판원성내피세포생장인자수평화내피조세포수량,결과현시2형당뇨병환자존재혈관신생장애,고령、HbA1c승고자급합병혈관병변환자경위명현.
Serum levels of human CXC-chemokine ligand 16,basic fibroblast growth factor,plateletderived endothelial cell growth factor,and number of endothelial progenitor cells were determined in 80 patients with type 2 diabetes mellitus and 40 normal control subjects.It was found that there were some disturbances of angiogenesis in diabetic patients.These abnormalities were more pronounced in these patients with old age,hyperglycemia,raised HbA1c,and presence of vascular diseases.