国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2008年
7期
507-509
,共3页
肿瘤转移%癌,非小细胞肺
腫瘤轉移%癌,非小細胞肺
종류전이%암,비소세포폐
Neoplasm,metastasis%Carcinoma,non-small-cell lung
检测非小细胞肺癌(NSCLC)微转移可以更准确地进行分期、指导治疗、判断预后.目前NSCLC微转移标志物的研究主要集中在细胞角蛋白(CK)19、人类肺组织特异性基因(LUNX)、癌胚抗原(CEA)mRNA、癌基因和抑癌基因等.NSCLC微转移部位的研究以淋巴结和骨髓多见,胸膜腔报道较少,外周血的报道逐渐增多.
檢測非小細胞肺癌(NSCLC)微轉移可以更準確地進行分期、指導治療、判斷預後.目前NSCLC微轉移標誌物的研究主要集中在細胞角蛋白(CK)19、人類肺組織特異性基因(LUNX)、癌胚抗原(CEA)mRNA、癌基因和抑癌基因等.NSCLC微轉移部位的研究以淋巴結和骨髓多見,胸膜腔報道較少,外週血的報道逐漸增多.
검측비소세포폐암(NSCLC)미전이가이경준학지진행분기、지도치료、판단예후.목전NSCLC미전이표지물적연구주요집중재세포각단백(CK)19、인류폐조직특이성기인(LUNX)、암배항원(CEA)mRNA、암기인화억암기인등.NSCLC미전이부위적연구이림파결화골수다견,흉막강보도교소,외주혈적보도축점증다.
Micrometastasis of carcinoma is one of the most significant pieces of evidence for molecular staging.Detection of micrometastasis of non-small-cell lung cancer plays a significant role in staging precisely,guiding treatment and predicting the prognosis of patients.This review is focused on the latest developments of markers such as CK19,LUNX,CEA mRNA,oncogene and anti-oncogene.The sites about micrometastasis of non-small-cell lung cancer are usually reported in lymph node and bone marrow,rarely in pleural cavity and increasingly in peripheral blood.