CAJ | 학술논문

神经发生是指神经干细胞自我增殖和分化成为新的神经元,并整合入神经网络的生物学过程,包括胚胎时期神经发牛和成体时期的神经发生.研究表明,微小RNA在神经发生中发挥着重要的调控作用.文章就近年来微小RNA在胚胎和成体神经发生调控中的分子机制以及脑缺血后神经发生过程中微小RNA的可能调控作用进行了综述.
신경발생시지신경간세포자아증식화분화성위신적신경원,병정합입신경망락적생물학과정,포괄배태시기신경발우화성체시기적신경발생.연구표명,미소RNA재신경발생중발휘착중요적조공작용.문장취근년래미소RNA재배태화성체신경발생조공중적분자궤제이급뇌결혈후신경발생과정중미소RNA적가능조공작용진행료종술.
Neurogenesis refers to a biological process of neural stem cells self-proliferate and differentiate into new neurons, and are integrated into the neural networks, including the embryonic neurogenesis and adult neurogenesis. Studies have suggested that microRNAs (miRNAs) play vital regulatory roles in neurogenesis. This article reviews the molecular mechanisms of miRNAs in the regulation of embryonic and adult neurogenesis as well as the possible regulatory roles of miRNAs in the process of neurogenesis after cerebral ischemia.