国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2011年
3期
195-198
,共4页
宋波%高远%谈颂%赵璐%李卓%卢甲盟%杨光%许予明
宋波%高遠%談頌%趙璐%李卓%盧甲盟%楊光%許予明
송파%고원%담송%조로%리탁%로갑맹%양광%허여명
卒中%脑缺血%功能性侧别%危险因素%预后
卒中%腦缺血%功能性側彆%危險因素%預後
졸중%뇌결혈%공능성측별%위험인소%예후
Stroke%Brain ischemia%Functional laterality%Risk factors%Prognosis
目的 探讨脑梗死病灶侧别对缺血性卒中患者转归的影响.方法 前瞻性连续纳入发病14 d内的前循环缺血性卒中患者,收集病例基本资料,如人口统计学资料、血管危险因素、临床表现、影像学资料、美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分和治疗措施等.采用6个月时改良Rankin量表(modified Raakin Scale,mRS)评价患者转归.结果 共纳/k407例患者,左侧半球卒qh230例(56.5%),右侧半球卒中177例(43.5%);转归良好(mRS评分<3分)318例,转归不良(mRS评分≥3分)89例.多变量logistic回归分析显示,年龄[优势比(odds ratio,OR)1.022,95%可信间区(confidence interval,Ci)1.001～1.043,P=0.040]、梗死病灶侧别(OR1.999,95% CI1.179～3.389,P=0.010)、发病至入院时间(OR1.006,95%(7/1.002～1.010.P=0·007)和NIHSS评分(OR1.147,95%CI1.095～1.203,P=0.000)是前循环缺血性卒中发病后6个月时转归的独立预测因素,右侧半球卒中转归较差.与左侧半球卒中相比,右侧半球卒中患者发病至入院的时间显著延迟(左侧:中位数12 h,平均22.72 h;右侧:中位数12 h,平均39.61 h,Z=-2.962.P=0·003).结论 左侧半球卒中发病后6个月时转归优于右侧半球卒中,可能与入院时间延迟有关.
目的 探討腦梗死病竈側彆對缺血性卒中患者轉歸的影響.方法 前瞻性連續納入髮病14 d內的前循環缺血性卒中患者,收集病例基本資料,如人口統計學資料、血管危險因素、臨床錶現、影像學資料、美國國立衛生研究院卒中量錶(National Institutes of Health Stroke Scale,NIHSS)評分和治療措施等.採用6箇月時改良Rankin量錶(modified Raakin Scale,mRS)評價患者轉歸.結果 共納/k407例患者,左側半毬卒qh230例(56.5%),右側半毬卒中177例(43.5%);轉歸良好(mRS評分<3分)318例,轉歸不良(mRS評分≥3分)89例.多變量logistic迴歸分析顯示,年齡[優勢比(odds ratio,OR)1.022,95%可信間區(confidence interval,Ci)1.001～1.043,P=0.040]、梗死病竈側彆(OR1.999,95% CI1.179～3.389,P=0.010)、髮病至入院時間(OR1.006,95%(7/1.002～1.010.P=0·007)和NIHSS評分(OR1.147,95%CI1.095～1.203,P=0.000)是前循環缺血性卒中髮病後6箇月時轉歸的獨立預測因素,右側半毬卒中轉歸較差.與左側半毬卒中相比,右側半毬卒中患者髮病至入院的時間顯著延遲(左側:中位數12 h,平均22.72 h;右側:中位數12 h,平均39.61 h,Z=-2.962.P=0·003).結論 左側半毬卒中髮病後6箇月時轉歸優于右側半毬卒中,可能與入院時間延遲有關.
목적 탐토뇌경사병조측별대결혈성졸중환자전귀적영향.방법 전첨성련속납입발병14 d내적전순배결혈성졸중환자,수집병례기본자료,여인구통계학자료、혈관위험인소、림상표현、영상학자료、미국국립위생연구원졸중량표(National Institutes of Health Stroke Scale,NIHSS)평분화치료조시등.채용6개월시개량Rankin량표(modified Raakin Scale,mRS)평개환자전귀.결과 공납/k407례환자,좌측반구졸qh230례(56.5%),우측반구졸중177례(43.5%);전귀량호(mRS평분<3분)318례,전귀불량(mRS평분≥3분)89례.다변량logistic회귀분석현시,년령[우세비(odds ratio,OR)1.022,95%가신간구(confidence interval,Ci)1.001～1.043,P=0.040]、경사병조측별(OR1.999,95% CI1.179～3.389,P=0.010)、발병지입원시간(OR1.006,95%(7/1.002～1.010.P=0·007)화NIHSS평분(OR1.147,95%CI1.095～1.203,P=0.000)시전순배결혈성졸중발병후6개월시전귀적독립예측인소,우측반구졸중전귀교차.여좌측반구졸중상비,우측반구졸중환자발병지입원적시간현저연지(좌측:중위수12 h,평균22.72 h;우측:중위수12 h,평균39.61 h,Z=-2.962.P=0·003).결론 좌측반구졸중발병후6개월시전귀우우우측반구졸중,가능여입원시간연지유관.
Objective To investigate the effect of the side of cerebral lesion on the outcome in patients with ischemic stroke.Methods A total of 407 consecutive anterior circulation ischemic stroke patients within 14 days after symptom onset were recruited prospectively.The basic data ofthe e,~ISes were collected,such as the National Institutes ofHealth Stroke Scale (NU-ISS)and the side ofcerebral lesion.The modified Rankin Scale(mRS)was used to evaluate the prognosis of the patients at 6 raomhs.Results Of the 407 patients recruited,230 patients (56.5%)Were left hemisphere stroke,177(43.5%)were fight hemisphere stroke.After multivariable logistic recession analysis,the age(odds ratio[OR]1.022,95% confidence interval[CI]1.001-1.043,P=0.040),the side of lesion(OR 1.999.95%CI1.179.3.389.P=0.010),the time from onset to admission(OR1.006,95%(7/1.002-1.010,P=0.007),the outcome of the anterior circulation ischcmic stroke at 6 months aftel"onset.The outcome of the right hemisphere stroke Was significantly worse than that of the left hemisphere stroke.The onset-admission time in patients with right hemisphere stroke(median 12 h,median 39.61 h)was significantly delayed compared to the patients with left hemisphere stroke(median 12 h,median 22.72 h;Z=-2.962,P=0.003).Condusions The outcome of the left hemisphere stroke at 6 months after onset is superior to the right hemisphere stroke,and it mau be associated with the delayed admission.
