CAJ | 학술논문

目的:研究木贼科植物笔管草(Equisetum debile)的化学成分.方法:采用硅胶、sephadex LH-20凝胶柱色谱进行分离纯化,通过理化方法和光谱分析鉴定化合物结构.结果:从笔管草全草乙酸乙酯和正丁醇提取物中分离得到4个megastigmane型化合物和4个黄酮苷，分别鉴定为blumenol A(1), corchoinoside C(2),sammangaoside A(3),(3S,5R,6R,7E,9S)-megastigmane-7-ene-3-hydroxy-5,6-epoxy-9-O-β-D-glucopyranoside(4)，山柰酚-3,7-双葡萄糖苷(5), camelliaside C(6),山柰酚-3-槐糖苷(7)and clematine(8).化合物1-4,6,8均为从木贼科植物首次分得.
목적:연구목적과식물필관초(Equisetum debile)적화학성분.방법:채용규효、sephadex LH-20응효주색보진행분리순화,통과이화방법화광보분석감정화합물결구.결과:종필관초전초을산을지화정정순제취물중분리득도4개megastigmane형화합물화4개황동감，분별감정위blumenol A(1), corchoinoside C(2),sammangaoside A(3),(3S,5R,6R,7E,9S)-megastigmane-7-ene-3-hydroxy-5,6-epoxy-9-O-β-D-glucopyranoside(4)，산내분-3,7-쌍포도당감(5), camelliaside C(6),산내분-3-괴당감(7)and clematine(8).화합물1-4,6,8균위종목적과식물수차분득.
AIM: To study the chemical constituents of Equisetum debile. METHODS: Compounds were isolated by column chromatography on silica gel, sephadex LH-20, ODS-18 and their structures were elucidated based on the spectroscopic methods including 2D NMR (COSY, HMQC, HMBC). RESULTS: Four megastigmane type compounds were isolated, one aglycone and three glucosides, identified as blumenol A (1), corchoinoside C (2), sammangaoside A (3), and (3S, 5R, 6R, 7E, 9S)-megastigmane-7-ene-3-hydroxy-5, 6-epoxy-9-O-β-D- glucopyranoside (4). Four flavonoid glycosides, kaempferol-3, 7-di-β-D-glucoside (5), camelliaside C (6), kaempferol 3-O-β-sophoroside (7), clematine (8) were also obtained from this plant. CONCLUSION: All megasigmane compounds and compound 6, 8 were obtained from Equisetaceae family for the first time.