CAJ | 학술논문

目的研究丙泊酚复合芬太尼或氯胺酮用于吸毒患者手术的麻醉处理.方法 516例吸毒患者按相同手术随机分为两组,均在术前持续微泵输注丙泊酚2.5～3 mg/kg,Ⅰ组258例,切皮开始前2分钟静注芬太尼2～3μg/kg;Ⅱ组258例,切皮开始前2分钟静注氯胺酮1 mg/kg,两组均术中酌情追加剂量.连续监测无创血压、心电图、脉搏血氧饱和度(SpO2).结果与术前比较,术中Ⅰ组平均动脉压(MAP)、心率(HR)显著下降,SpO2差异无显著性(P＞0.05);Ⅱ组平均动脉压(MAP)、心率(HR)明显增高(P＜0.05),SpO2差异无显著性(P＞0.05),两组术程均未出现戒断症状,效果满意.结论丙泊酚复合芬太尼或氯胺酮不仅可以防治戒断症状,而且可以增强麻醉效果.术中要注意加强监护,维护呼吸循环的稳定.
목적 연구병박분복합분태니혹록알동용우흡독환자수술적마취처리.방법 516례흡독환자안상동수술수궤분위량조,균재술전지속미빙수주병박분2.5～3 mg/kg,Ⅰ조258례,절피개시전2분종정주분태니2～3μg/kg;Ⅱ조258례,절피개시전2분종정주록알동1 mg/kg,량조균술중작정추가제량.련속감측무창혈압、심전도、맥박혈양포화도(SpO2).결과 여술전비교,술중Ⅰ조평균동맥압(MAP)、심솔(HR)현저하강,SpO2차이무현저성(P＞0.05);Ⅱ조평균동맥압(MAP)、심솔(HR)명현증고(P＜0.05),SpO2차이무현저성(P＞0.05),량조술정균미출현계단증상,효과만의.결론 병박분복합분태니혹록알동불부가이방치계단증상,이차가이증강마취효과.술중요주의가강감호,유호호흡순배적은정.
Objective To investigate the effect of propofol combined with fentanil or ketamine for anesthesia in drug abusers. Methods 516 drug abusers were randomly assgined to receive continuous preoperative injection of propofol of 2.5-3 mg/kg and then either intravenous fentanil of 2-3 μg/kg (258patients, group Ⅰ ) or ketamine of lng/kg (258 patients, group Ⅱ). Additional doses of fentanil or ketamine were added when necessary. Blood pressure, ECG and SpO2 were continuously monitored. Results As compared with the baseline values, MAP and HR significantly decreased in group Ⅰ (P＜ 0.05), while increased in group Ⅱ (P＜0.05); there was no significant difference in SpO2. No abstinent symptoms occurred in all the patients. Conclusions Propofol combined with fentanil or ketamine can not only prevent and treat abstinent symptoms but also enhance anesthestic effect. lntraoperative monitoring should be enhanced and the stability of respiration and circulation system should be maintained.