中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2010年
11期
1006-1010
,共5页
视网膜静脉闭塞%黄斑水肿%视敏度%光感受器%体层摄影术,光学相干
視網膜靜脈閉塞%黃斑水腫%視敏度%光感受器%體層攝影術,光學相榦
시망막정맥폐새%황반수종%시민도%광감수기%체층섭영술,광학상간
Retinal vein occlusion%Macular edema%Visual acuity%Photoreceptors%Tomography,optical coherence
目的 探讨视网膜分支静脉阻塞(BRVO)伴黄斑囊样水肿患者的光感受器细胞层变化与视力之间的关系.方法 回顾性病例系列研究.对2008年1月至2010年1月就诊的41例(41只眼)BRVO伴黄斑囊样水肿患者的临床资料进行回顾性分析.纳入对象均采用频域相干光断层扫描(OCT)仪测量黄斑中心凹神经上皮层厚度、中心凹囊腔下光感受器细胞层厚度、中心凹水肿囊腔的高度与水平宽度.根据患者光感受器细胞内外节(IS-OS)层的检测情况,分为3组进行分析,完全连续组8例,不完全连续组19例,完全缺失组14例.采用Spearman相关检验法分析各项检测参数与视力的相关性,应用LSD检验法比较不同IS-OS组间患者logMAR视力差异.结果 41例(41只眼)BRVO黄斑囊样水肿患者黄斑中心凹神经上皮层厚度平均(484.71±131.86)μm,光感受器细胞层厚度平均(92.04±45.53)μm,中心凹囊腔面积平均772.59 μm×362.17 μm.经Spearman相关性检验,上述检测参数中仅光感受器细胞层厚度与logMAR视力相关(r=-0.373,P=0.016).IS-OS层完全缺失组患者的logMAR视力与完全连续组和不完全连续组间差异均有统计学意义(P=0.030,0.003),而完全连续组与不完全连续组间差异无统计学意义(P=0.750).结论 BRVO伴黄斑囊样水肿患者的视力随白身光感受器细胞层厚度的增加而提高,IS-OS层完全缺失的患者较存在IS-OS层的患者视力差.
目的 探討視網膜分支靜脈阻塞(BRVO)伴黃斑囊樣水腫患者的光感受器細胞層變化與視力之間的關繫.方法 迴顧性病例繫列研究.對2008年1月至2010年1月就診的41例(41隻眼)BRVO伴黃斑囊樣水腫患者的臨床資料進行迴顧性分析.納入對象均採用頻域相榦光斷層掃描(OCT)儀測量黃斑中心凹神經上皮層厚度、中心凹囊腔下光感受器細胞層厚度、中心凹水腫囊腔的高度與水平寬度.根據患者光感受器細胞內外節(IS-OS)層的檢測情況,分為3組進行分析,完全連續組8例,不完全連續組19例,完全缺失組14例.採用Spearman相關檢驗法分析各項檢測參數與視力的相關性,應用LSD檢驗法比較不同IS-OS組間患者logMAR視力差異.結果 41例(41隻眼)BRVO黃斑囊樣水腫患者黃斑中心凹神經上皮層厚度平均(484.71±131.86)μm,光感受器細胞層厚度平均(92.04±45.53)μm,中心凹囊腔麵積平均772.59 μm×362.17 μm.經Spearman相關性檢驗,上述檢測參數中僅光感受器細胞層厚度與logMAR視力相關(r=-0.373,P=0.016).IS-OS層完全缺失組患者的logMAR視力與完全連續組和不完全連續組間差異均有統計學意義(P=0.030,0.003),而完全連續組與不完全連續組間差異無統計學意義(P=0.750).結論 BRVO伴黃斑囊樣水腫患者的視力隨白身光感受器細胞層厚度的增加而提高,IS-OS層完全缺失的患者較存在IS-OS層的患者視力差.
목적 탐토시망막분지정맥조새(BRVO)반황반낭양수종환자적광감수기세포층변화여시력지간적관계.방법 회고성병례계렬연구.대2008년1월지2010년1월취진적41례(41지안)BRVO반황반낭양수종환자적림상자료진행회고성분석.납입대상균채용빈역상간광단층소묘(OCT)의측량황반중심요신경상피층후도、중심요낭강하광감수기세포층후도、중심요수종낭강적고도여수평관도.근거환자광감수기세포내외절(IS-OS)층적검측정황,분위3조진행분석,완전련속조8례,불완전련속조19례,완전결실조14례.채용Spearman상관검험법분석각항검측삼수여시력적상관성,응용LSD검험법비교불동IS-OS조간환자logMAR시력차이.결과 41례(41지안)BRVO황반낭양수종환자황반중심요신경상피층후도평균(484.71±131.86)μm,광감수기세포층후도평균(92.04±45.53)μm,중심요낭강면적평균772.59 μm×362.17 μm.경Spearman상관성검험,상술검측삼수중부광감수기세포층후도여logMAR시력상관(r=-0.373,P=0.016).IS-OS층완전결실조환자적logMAR시력여완전련속조화불완전련속조간차이균유통계학의의(P=0.030,0.003),이완전련속조여불완전련속조간차이무통계학의의(P=0.750).결론 BRVO반황반낭양수종환자적시력수백신광감수기세포층후도적증가이제고,IS-OS층완전결실적환자교존재IS-OS층적환자시력차.
Objective To study the correlation of visual acuity and photoreceptor in eyes with persistent cystoid macular edema associated with branch retinal vein occlusion (BRVO). Methods It was a retrospective case series study. Medical records of 41 patients ( 41 eyes ) with persistent cystoid macular edema secondary to BRVO diagnosed in Department of Ophthalmology, Peking Union Medical College Hospital from January 2008 to January 2010 were studied retrospectively. On the images obtained by spectral-domain OCT, the thickness of foveal neurosensory retina and photoreceptor layer that was beneath the foveal cystoid spaces, and the transverse length and height of foveal cystoid spaces were measured. The status of the junction between inner and outer segments of the photoreceptors (IS-OS) in the fovea was also assessed. The correlations between the parameters above and visual acuity were analyzed. Results The average foveal neurosensory thickness was ( 484.71 ± 131.86) μm, the photoreceptor layer thickness was (92.04 : 45. 53 ) μm and the size of foveal cavity was 772.59 μm ×362.17 μm. By the Spearman's rank correlation analysis, among the parameters above, only photoreceptor layer thickness showed correlation with logMAR visual acuity (r = -0. 373, P = 0. 016 ), while other parameters showed no correlation with logMAR visual acuity. Cases were classified as three groups according to the status of IS-OS layer:continuous group(8 cases), discontinuous group( 19 cases) and interrupted group( 14 cases). LogMAR visual acuity in these eyes with an interrupted IS-OS line in the fovea was significantly worse than that in eyes with a continuous or discontinuous IS-OS line ( P = 0. 030 and 0. 003, respectively). There was no statistical difference between continuous and discontinuous group ( P = 0. 750 ). Conclusions In patients with persistent cystoid macular edema associated with BRVO, the thickness of the foveal photoreceptor layer are positively associated with visual acuity, and the eyes without IS-OS layer have worse visual acuity than eyes with IS-OS layer.
