中华胃肠外科杂志
中華胃腸外科雜誌
중화위장외과잡지
CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
2011年
5期
340-242
,共-97页
葛军娜%于健春%康维明%马志强%古应超
葛軍娜%于健春%康維明%馬誌彊%古應超
갈군나%우건춘%강유명%마지강%고응초
消化系统肿瘤%贫血%血红蛋白%性别%年龄
消化繫統腫瘤%貧血%血紅蛋白%性彆%年齡
소화계통종류%빈혈%혈홍단백%성별%년령
Digestive system neoplasms%Anemia%Hemoglobin%Gender%Age
目的 调查总结消化系癌的贫血发生情况.方法 回顾性收集2000年1月至2009年6月在北京协和医院住院治疗且明确诊断的消化系癌10 218例,其中食管癌1118例,胃癌2418例,十二指肠癌134例,小肠癌85例,肝细胞癌1508例,胆管癌546例,胰腺癌1242例,结肠癌1582例,直肠癌1585例.对其贫血发生情况进行分析.结果 按照中国贫血标准(血红蛋白小于120 g/L),接受调查的患者中消化系癌贫血发生率为27.5%(2813/10 218),不同肿瘤贫血发生率由高至低依次为小肠癌(64.7%)、十二指肠癌(60.5%)、结肠癌(42.6%)、胆管癌(36.6%)、胃癌(33.3%)、胰腺癌(22.6%)、直肠癌(20.4%)、肝细胞癌(18.7%)和食管癌(10.0%).在胃癌、胆管癌、胰腺癌、结肠癌和直肠癌中,贫血以高龄患者多见;在小肠癌和胆管癌,贫血以男性患者多见.但在肝细胞癌和胰腺癌中则以女性患者多见(P<0.05).结论 消化系癌易发生贫血,其中以十二指肠癌和小肠癌发生率最高,胃癌和结肠癌次之,食管癌贫血发生率最低.在某些消化系癌中,贫血发生可能与年龄和性别有关.
目的 調查總結消化繫癌的貧血髮生情況.方法 迴顧性收集2000年1月至2009年6月在北京協和醫院住院治療且明確診斷的消化繫癌10 218例,其中食管癌1118例,胃癌2418例,十二指腸癌134例,小腸癌85例,肝細胞癌1508例,膽管癌546例,胰腺癌1242例,結腸癌1582例,直腸癌1585例.對其貧血髮生情況進行分析.結果 按照中國貧血標準(血紅蛋白小于120 g/L),接受調查的患者中消化繫癌貧血髮生率為27.5%(2813/10 218),不同腫瘤貧血髮生率由高至低依次為小腸癌(64.7%)、十二指腸癌(60.5%)、結腸癌(42.6%)、膽管癌(36.6%)、胃癌(33.3%)、胰腺癌(22.6%)、直腸癌(20.4%)、肝細胞癌(18.7%)和食管癌(10.0%).在胃癌、膽管癌、胰腺癌、結腸癌和直腸癌中,貧血以高齡患者多見;在小腸癌和膽管癌,貧血以男性患者多見.但在肝細胞癌和胰腺癌中則以女性患者多見(P<0.05).結論 消化繫癌易髮生貧血,其中以十二指腸癌和小腸癌髮生率最高,胃癌和結腸癌次之,食管癌貧血髮生率最低.在某些消化繫癌中,貧血髮生可能與年齡和性彆有關.
목적 조사총결소화계암적빈혈발생정황.방법 회고성수집2000년1월지2009년6월재북경협화의원주원치료차명학진단적소화계암10 218례,기중식관암1118례,위암2418례,십이지장암134례,소장암85례,간세포암1508례,담관암546례,이선암1242례,결장암1582례,직장암1585례.대기빈혈발생정황진행분석.결과 안조중국빈혈표준(혈홍단백소우120 g/L),접수조사적환자중소화계암빈혈발생솔위27.5%(2813/10 218),불동종류빈혈발생솔유고지저의차위소장암(64.7%)、십이지장암(60.5%)、결장암(42.6%)、담관암(36.6%)、위암(33.3%)、이선암(22.6%)、직장암(20.4%)、간세포암(18.7%)화식관암(10.0%).재위암、담관암、이선암、결장암화직장암중,빈혈이고령환자다견;재소장암화담관암,빈혈이남성환자다견.단재간세포암화이선암중칙이녀성환자다견(P<0.05).결론 소화계암역발생빈혈,기중이십이지장암화소장암발생솔최고,위암화결장암차지,식관암빈혈발생솔최저.재모사소화계암중,빈혈발생가능여년령화성별유관.
Objective To study the prevalence of tumor related anemia in patients with cancer in the digestive system. Methods A total of of 10 218 inpatients were diagnosed with cancer in the digestive system at the Peking Union Hospital from Janary 2000 to June 2009, which included esophageal cancer(n=1118), gastric cancer(n=2418), carcinoma of duodenum(n=134), carcinoma of small intestine(n=85), hepatocellular cancer(n= 1508), cholangiocarcinoma (n=546), pancreatic cancer (n=1242), colon cancer (n=1582), and rectal cancer (n=1585). Patients with hemolytic anemia or hepatorenal dysfunction were excluded. Data pertaining to sex, age and hemoglobin were obtained by chart review. Results According to the China criteria of anemia, the overall anemia rate was 27.5% (2813/10 218). The prevalence of anemia was 64.7% for small bowel cancer, 60.5% for duodenal cancer, 42.6% for colon cancer, 36.6% for cholangiocarcinoma, 33.3% for gastric cancer, 22.6% for pancreatic cancer, 20.4% for rectal cancer, 18.7% for hepatocellular cancer, and 10.0% for esophageal cancer. Anemia was more common in older patients in those with gastric cancer, cholangiocarcinoma, pancreatic cancer, colon cancer and rectal cancer. There were more male anemic patients in those with cancer in the small intestine or cholangiocarcinoma. However, females were more commonly seen in those with hepatocellular cancer or pancreatic cancer. Conclusions Anemia is common in patients with cancer in the digestive system. The prevalence of anemia is higher in patients with cancer in the duodenum carcinoma or small intestine, followed by colon cancer and gastric cancer, and then esophageal cancer. Anemia may be associated with age or gender in some types of cancer in the digestive system.
