中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2009年
4期
623-624
,共2页
妊娠并发症%狼疮肾炎%妊娠结局%时间安排
妊娠併髮癥%狼瘡腎炎%妊娠結跼%時間安排
임신병발증%랑창신염%임신결국%시간안배
Pregnancy complications%Lupus nephritis%Pregnancy Outcome%Time management
目的 探讨妊娠合并狼疮肾炎的妊娠时机、预后与孕产期处理.方法 回顾性分析妊娠合并狼疮肾炎9例临床资料.结果 9例妊娠合并狼疮肾炎患者,在孕产期均出现不同程度的高血压、蛋白尿、肾功能受损和血清学异常等,其中流产2例,死胎1例,早产儿4例,足月产儿2例,未出现新生儿畸形和死亡,孕产妇无产后出血或死亡.活动期妊娠2例,妊娠丢失率为100%,其中1例出现病情恶化.在控制期和缓解期妊娠7例,妊娠丢失率为11.1%,前者与后者相比明显升高(P<0.05).结论 狼疮肾炎患者宜在疾病缓解期妊娠,孕产期正确使用肾上腺皮质激素,并加强母婴监护,才能够获得妊娠机会及安全渡过孕产期.
目的 探討妊娠閤併狼瘡腎炎的妊娠時機、預後與孕產期處理.方法 迴顧性分析妊娠閤併狼瘡腎炎9例臨床資料.結果 9例妊娠閤併狼瘡腎炎患者,在孕產期均齣現不同程度的高血壓、蛋白尿、腎功能受損和血清學異常等,其中流產2例,死胎1例,早產兒4例,足月產兒2例,未齣現新生兒畸形和死亡,孕產婦無產後齣血或死亡.活動期妊娠2例,妊娠丟失率為100%,其中1例齣現病情噁化.在控製期和緩解期妊娠7例,妊娠丟失率為11.1%,前者與後者相比明顯升高(P<0.05).結論 狼瘡腎炎患者宜在疾病緩解期妊娠,孕產期正確使用腎上腺皮質激素,併加彊母嬰鑑護,纔能夠穫得妊娠機會及安全渡過孕產期.
목적 탐토임신합병랑창신염적임신시궤、예후여잉산기처리.방법 회고성분석임신합병랑창신염9례림상자료.결과 9례임신합병랑창신염환자,재잉산기균출현불동정도적고혈압、단백뇨、신공능수손화혈청학이상등,기중유산2례,사태1례,조산인4례,족월산인2례,미출현신생인기형화사망,잉산부무산후출혈혹사망.활동기임신2례,임신주실솔위100%,기중1례출현병정악화.재공제기화완해기임신7례,임신주실솔위11.1%,전자여후자상비명현승고(P<0.05).결론 랑창신염환자의재질병완해기임신,잉산기정학사용신상선피질격소,병가강모영감호,재능구획득임신궤회급안전도과잉산기.
Objective To study the outcome of pregnancy with lupus nephritis. Methods The clinical data of 9 pregnancies with lupus nephritis were retrospectively malyzed. Results Hypertension,proteinuria,injured renal function and abnormal serological marker were complicated with nine patients with lupus nephritis in pregnancy. The outcome of pregnancy was as following:abortion 2 cases,stillbirth 1 case,premature delivery 4 cases,term delivery 2 cases. All neonate survived without malformation. There was no postpartum hemorrhage or death. Patients with active SLE had very high fetal mortality( 100% ). And SLE got worsen in 50% of them. However,fetal mortality rate in pa-tients with controlled or quiescent SLE was 11.1% ,which was much lower than it in other patients(P<0.05). Con-clusion Lupus nephritis should be controlled before pregnancy. Pregnancy outcome could be improved by careful multidisciplinary monitoring and proper usage of adrenal cortical hormone.
