中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
CHINESE PEDIATRIC EMERGENCY MEDICINE
2007年
z1期
13-14
,共2页
缺氧缺血性脑病%新生儿
缺氧缺血性腦病%新生兒
결양결혈성뇌병%신생인
Hypoxic-ischemic encephalopathy%Neonate
目的 对HIE所致脑损伤的病因进行临床分析与研究,评估HIE脑损伤程度及预后.方法 回顾分析本院117例HIE新生儿的一般临床资料、血气、血糖、血生化、头颅CT、随访结果和预后.结果 HIE轻、中、重度三组患儿之间体重及胎龄均无显著差异.日龄重度组明显增大,而Apgar评分减低,组间方差分析有显著差异(P＜0.01).血生化指标变化,pH及PaCO2组间有差异性,重度组Glu及BE减少明显,肾功能(BUN、Cr)、心肌酶(CK-MB、CK)在中、重度组均有不同程度升高,组间方差分析有显著意义(P＜0.01).头颅CT异常率82.6%,而且随着病情加重异常率增加.结论 HIE轻度者预后良好,中度组如果治疗得当,疗程足够,绝大多数远期随访预后较好.
目的 對HIE所緻腦損傷的病因進行臨床分析與研究,評估HIE腦損傷程度及預後.方法 迴顧分析本院117例HIE新生兒的一般臨床資料、血氣、血糖、血生化、頭顱CT、隨訪結果和預後.結果 HIE輕、中、重度三組患兒之間體重及胎齡均無顯著差異.日齡重度組明顯增大,而Apgar評分減低,組間方差分析有顯著差異(P＜0.01).血生化指標變化,pH及PaCO2組間有差異性,重度組Glu及BE減少明顯,腎功能(BUN、Cr)、心肌酶(CK-MB、CK)在中、重度組均有不同程度升高,組間方差分析有顯著意義(P＜0.01).頭顱CT異常率82.6%,而且隨著病情加重異常率增加.結論 HIE輕度者預後良好,中度組如果治療得噹,療程足夠,絕大多數遠期隨訪預後較好.
목적 대HIE소치뇌손상적병인진행림상분석여연구,평고HIE뇌손상정도급예후.방법 회고분석본원117례HIE신생인적일반림상자료、혈기、혈당、혈생화、두로CT、수방결과화예후.결과 HIE경、중、중도삼조환인지간체중급태령균무현저차이.일령중도조명현증대,이Apgar평분감저,조간방차분석유현저차이(P＜0.01).혈생화지표변화,pH급PaCO2조간유차이성,중도조Glu급BE감소명현,신공능(BUN、Cr)、심기매(CK-MB、CK)재중、중도조균유불동정도승고,조간방차분석유현저의의(P＜0.01).두로CT이상솔82.6%,이차수착병정가중이상솔증가.결론 HIE경도자예후량호,중도조여과치료득당,료정족구,절대다수원기수방예후교호.
Objective To study the clinical analysis in the neonatal hypoxic-ischemic encephalopathy (HIE)for evealuation of the severity of brain injury and prognosis. Methods The manifestation,laboratory findings,outcomes of 117 HIE were analyzed. Results Manifestations of HIE in 117 infants included 3 groups(minor level,moderate level,severe level). There was no significant difference in the weight and gestation-age among 3 groups.Scores of Apgar lowing,which Was marked in the severe level(P＜0.01). There was significant difference in the level of pH and PaCO2(P＜0.01). There was significant difference in the level of blood GLU and BE reduced aboviusly in the severe level,and in the level of BUN,CK-MB,CK increased aboviusly in the moderate and severe level,among all(P＜0.01). 69 patients were taked CT on the brain,the abnormal rate of which was 82.6%. The abnormal rate of CT on the brain increased 100% changing with the severity of brain injury on HIE especially in the moderate and severe level. Conclusion The prognosis of the minor level of brain injury on HIE is the best. The prognosis of the moderate-level group who was treated reasonably and enough,is better mostly.
