CAJ | 학술논문

凝血因子XI缺陷症（FactorXIdenciency）是荷斯坦牛的一种常染色体单基因控制的隐性遗传缺陷。该病的遗传基础是由位于牛第27号染色体的凝血因子XI基因外显子12上发生的一段76bp序列插入。本研究采用PCR方法对我国13个主要公牛站的571头荷斯坦公牛的凝血因子XI基因进行了全面检测，未发现隐性有害基因携带者和纯合个体。
응혈인자XI결함증（FactorXIdenciency）시하사탄우적일충상염색체단기인공제적은성유전결함。해병적유전기출시유위우우제27호염색체적응혈인자XI기인외현자12상발생적일단76bp서렬삽입。본연구채용PCR방법대아국13개주요공우참적571두하사탄공우적응혈인자XI기인진행료전면검측，미발현은성유해기인휴대자화순합개체。
Factor XI deficiency is an autosomal recessive inherited defect in Holstein cattle. Affected animals showed a number of symptoms adversely affecting the reproductive performances of the cows and appeared more susceptible to diseases. The mechanism on this deficiency is the mutation for a 76 base insertion into exon 12 of FXI gene that causes Factor XI deficiency. In this study, based on the PCR method, 571 bulls from 13 bull stations were detected for the genotypes of Factor XI deficiency. No carrier bulls of Factor XI deficiency were found.