CAJ | 학술논문

阿德呋啉属核苷酸类化合物，通过干扰球虫嘌呤代谢而发挥抗球虫作用。为评价其抗球虫效果，将该药分别以30、60、90mg／kg浓度添加于饲料中治疗人工感染鸡球虫病，同时以磺胺喹嗯啉500mg／kg浓度拌料给药作为对照。结果表明，阿德呋啉高剂量组（90mg／kg）具有良好的抗球虫效果，其抗球虫指数为183．2；中、低剂量组（30、60mg／kg）与磺胺喹嚼啉则疗效很差，抗球虫指数均在120以下。故建议阿德呋啉治疗剂量为90mg／kg。
아덕부람속핵감산류화합물，통과간우구충표령대사이발휘항구충작용。위평개기항구충효과，장해약분별이30、60、90mg／kg농도첨가우사료중치료인공감염계구충병，동시이광알규은람500mg／kg농도반료급약작위대조。결과표명，아덕부람고제량조（90mg／kg）구유량호적항구충효과，기항구충지수위183．2；중、저제량조（30、60mg／kg）여광알규작람칙료효흔차，항구충지수균재120이하。고건의아덕부람치료제량위90mg／kg。
Adprin is a compound of nucleoside with anticoccidiosis activity by interfering with the purine metabolism pathway of coccidia. Adprin was used to feed at the dose of 30, 60, 90 mg/kg for evaluating the anticoccidial efficacy chicken of artificial coccidiosis. Sulfaquinoxalinum was used for control. The results revealed that the dose of 90 mg/kg adprin had high efficacy with the ACI 183.2. But the moderate and lower dose of adprin and sulfaquinoxalinum had low efficacy with the ACI below 120. So the dose of 90 mg/kg was recommended.