世界农药
世界農藥
세계농약
Pesticides of world
2009年
z1期
1-7
,共7页
李忠%邵旭升%田忠贞%黄青春%钱旭红
李忠%邵旭升%田忠貞%黃青春%錢旭紅
리충%소욱승%전충정%황청춘%전욱홍
neonicotinoids%configuration%imidacloprid%insecticidal activities
Neonicotinoids,targeting insect nicotinic acetylcholine receptors (nAChRs),has attracted considerable attentions for decades.To explore the influence of configuration of-NO2 on bioactivities and search for compounds with higher activities,some classes of neonicotinoids containing tetrahydropyridine or bukyl substituent were synthesized,in which the -NO2 and pyridine was kept in same side of nitromethylene.Neonicotinoids with tetrahydropyridine fixed cis configuration exhibited high activities against cowpea aphids and brown planthopper (Nilaparvata lugens),furthermore,some compounds showed higher insecticidal activities against imidacloprid-resistant brown planthopper than imidacloprid.However,the open-chain analogues with tetrahydropyridine fixed cis configuration only exhibited some knockdown activities against cowpea aphids.Neonicotinoids with bulky substituents fixed cis configuration compounds exhibited higher insecticidal activities against cowpea aphids,armyworm and Nephotettix bipunctatus (Fabricius).