中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2009年
16期
74-76
,共3页
毛和平%刘光斌%刘效栓%宋京都%滕宝霞%刘玉玲
毛和平%劉光斌%劉效栓%宋京都%滕寶霞%劉玉玲
모화평%류광빈%류효전%송경도%등보하%류옥령
舒阴洗液%皮肤急性毒性%皮肤刺激性%皮肤过敏反应%黏膜刺激性
舒陰洗液%皮膚急性毒性%皮膚刺激性%皮膚過敏反應%黏膜刺激性
서음세액%피부급성독성%피부자격성%피부과민반응%점막자격성
Shuyin Lotions%Acute cutaneous toxicity%skin irritation%Skin allergy reaction%mucosal irritation
目的 对舒阴洗液进行了部分动物实验研究,包括皮肤急性毒性实验、皮肤刺激性实验、皮肤过敏性实验及黏膜刺激性实验,以了解其安全性.方法 将不同剂量的舒阴洗液用于大耳白兔背部完整或破损去毛区皮肤,观察其产生急性毒性和皮肤刺激性情况;采用致敏与激发接触舒阴洗液,观察豚鼠过敏情况;将舒阴洗液注入大耳白兔的阴道中,观察大耳白兔阴道黏膜的情况.结果 舒阴洗液未产生皮肤急性毒性和刺激性;也未产生阴道黏膜刺激性;反复致敏后无皮肤与全身过敏反应.结论 舒阴洗液是安全的新型外用洗剂.
目的 對舒陰洗液進行瞭部分動物實驗研究,包括皮膚急性毒性實驗、皮膚刺激性實驗、皮膚過敏性實驗及黏膜刺激性實驗,以瞭解其安全性.方法 將不同劑量的舒陰洗液用于大耳白兔揹部完整或破損去毛區皮膚,觀察其產生急性毒性和皮膚刺激性情況;採用緻敏與激髮接觸舒陰洗液,觀察豚鼠過敏情況;將舒陰洗液註入大耳白兔的陰道中,觀察大耳白兔陰道黏膜的情況.結果 舒陰洗液未產生皮膚急性毒性和刺激性;也未產生陰道黏膜刺激性;反複緻敏後無皮膚與全身過敏反應.結論 舒陰洗液是安全的新型外用洗劑.
목적 대서음세액진행료부분동물실험연구,포괄피부급성독성실험、피부자격성실험、피부과민성실험급점막자격성실험,이료해기안전성.방법 장불동제량적서음세액용우대이백토배부완정혹파손거모구피부,관찰기산생급성독성화피부자격성정황;채용치민여격발접촉서음세액,관찰돈서과민정황;장서음세액주입대이백토적음도중,관찰대이백토음도점막적정황.결과 서음세액미산생피부급성독성화자격성;야미산생음도점막자격성;반복치민후무피부여전신과민반응.결론 서음세액시안전적신형외용세제.
Objective The partial animal experiments on Shuyin Lotions have been done, including tests of acute cutaneous toxicity,skin irritation,skin allergy reaction and mucosal irritation for understanding safety.Methods Shuyin Lotions was spread on the integral and damaged skins that hairs were cut off in the back of rabbit.It was observed whether Shuyin Lotions could induce acute toxicity and skin irritation. The allergy reactions of guinea pigs were watched by sensitizing and challenge contact to Shuyin Lotions. Shuyin Lotions was injected in vagina of rabbit,the mucosal irritation of Shuyin Lotions was observed. Results The results indicate that Shuyin Lotions does not induce acute toxicity and skin irritation and mucosal irritation, and not cause skin and whole body allergy reaction by manytimes sensitization.Conclusion Shuyin Lotions was a newly lotions which could be used safely and handily.
