CAJ | 학술논문

目的：探讨萌动激活赤灵芝孢子粉对小鼠脾细胞IL-2分泌和脾淋巴细胞转化增殖的影响。方法：实验小鼠随机分成实验组(低剂量组4g/kg/d：高剂量组：8g/kg/d)和对照组(与实验组用同体积的生理盐水)，连续用药10天。用3H—TdR掺入法进行检测。结果：与对照组相比萌动激活赤灵芝孢子粉对小鼠脾细胞IL-2分泌有明显促进作用并能明显提高小鼠脾淋巴细胞转化增殖，并有一定的量效关系。结论：萌动激活赤灵芝孢子粉对小鼠免疫功能有明显的促进作用，这可能与其促进细胞因子的分泌和淋巴细胞转化增殖有关。
목적：탐토맹동격활적령지포자분대소서비세포IL-2분비화비림파세포전화증식적영향。방법：실험소서수궤분성실험조(저제량조4g/kg/d：고제량조：8g/kg/d)화대조조(여실험조용동체적적생리염수)，련속용약10천。용3H—TdR참입법진행검측。결과：여대조조상비맹동격활적령지포자분대소서비세포IL-2분비유명현촉진작용병능명현제고소서비림파세포전화증식，병유일정적량효관계。결론：맹동격활적령지포자분대소서면역공능유명현적촉진작용，저가능여기촉진세포인자적분비화림파세포전화증식유관。
To explore the action of actively germinating ganoderma spore onthe secretion of IL-2 and the transformation and proliferation of mouse splenocyte.Methods:3H-TdR incorporation scintillation count assays. Results: Compared with the control,the actively germinating ganoderma spore not only dramatically increased the secretion of IL-2 but also enhanced the transformation and proliferation of mouse splenocyte with dose manner. The actively germinating ganoderma spore possesses obviously immuno-promoting effect on mouse immune system and this effect might be related with the secretion of cytokines and the proliferation and transformation of lymphocyte