天津医科大学学报
天津醫科大學學報
천진의과대학학보
JOURNAL OF TIANJIN MEDICAL UNIVERSITY
2001年
1期
54-55
,共2页
口服避孕药%妊娠高血压史%女性脑出血%病例对照研究
口服避孕藥%妊娠高血壓史%女性腦齣血%病例對照研究
구복피잉약%임신고혈압사%녀성뇌출혈%병례대조연구
目的：探讨口服避孕药及妊娠情况与脑出血的关系。方法：采用配比病例对照研究方法，对145例经颅脑[摘要]目的：探讨口服避孕药及妊娠情况与脑出血的关系。方法：采用配比病例对照研究方法，对145例经颅脑CT确诊的女性脑出血病例均配以医院对照，应用条件Logistic回归分析。结果：口服避孕药对女性脑出血的OR为：2.50(95％CI：1.49～8.20)，按高血压病史调整后为3.56(95％CI：1.04～17.82)。单因素分析时，妊娠高血压史可增加患脑出血的危险性，OR为3.15(95％CI：1.75～5.65)，按高血压病史调整后其作用失去显著意义。结论：口服避孕药很可能是女性脑出血的独立的危险因素，提示妊娠高血压可能是借助于影响血压间接地增加了患脑出血的危险性。未发现妊娠次数、初末产年龄及月经初潮年龄与女性脑出血有关。
目的：探討口服避孕藥及妊娠情況與腦齣血的關繫。方法：採用配比病例對照研究方法，對145例經顱腦[摘要]目的：探討口服避孕藥及妊娠情況與腦齣血的關繫。方法：採用配比病例對照研究方法，對145例經顱腦CT確診的女性腦齣血病例均配以醫院對照，應用條件Logistic迴歸分析。結果：口服避孕藥對女性腦齣血的OR為：2.50(95％CI：1.49～8.20)，按高血壓病史調整後為3.56(95％CI：1.04～17.82)。單因素分析時，妊娠高血壓史可增加患腦齣血的危險性，OR為3.15(95％CI：1.75～5.65)，按高血壓病史調整後其作用失去顯著意義。結論：口服避孕藥很可能是女性腦齣血的獨立的危險因素，提示妊娠高血壓可能是藉助于影響血壓間接地增加瞭患腦齣血的危險性。未髮現妊娠次數、初末產年齡及月經初潮年齡與女性腦齣血有關。
목적：탐토구복피잉약급임신정황여뇌출혈적관계。방법：채용배비병례대조연구방법，대145례경로뇌[적요]목적：탐토구복피잉약급임신정황여뇌출혈적관계。방법：채용배비병례대조연구방법，대145례경로뇌CT학진적녀성뇌출혈병례균배이의원대조，응용조건Logistic회귀분석。결과：구복피잉약대녀성뇌출혈적OR위：2.50(95％CI：1.49～8.20)，안고혈압병사조정후위3.56(95％CI：1.04～17.82)。단인소분석시，임신고혈압사가증가환뇌출혈적위험성，OR위3.15(95％CI：1.75～5.65)，안고혈압병사조정후기작용실거현저의의。결론：구복피잉약흔가능시녀성뇌출혈적독립적위험인소，제시임신고혈압가능시차조우영향혈압간접지증가료환뇌출혈적위험성。미발현임신차수、초말산년령급월경초조년령여녀성뇌출혈유관。
Objective: To investigate the correlations between cerebral hemorrhage in women and oral contrceptives and pregnant status. Methods:A1:1 pair matched case control study was conducted on145 women with cerebral hemorrhage diagnosed by CT scan of the head and the same number of hospital controls, using conditional logistic regression analysis. Results: Odds ratio(OR) for OC was 3.50(95% CI:1.49～8.20), after adjusting by the history of hypertension the OR was 3.56 (95% CI:1.04～17.82). Single factor analysis revealed history of pregnant hypertension increased the risk of cerebral hemorrhage the OR were 3.15(95%CI:1.75～5.65) , after adjusting by the history of hypertension the effects of pregnant hypertension became non-significant. Conclusion: Use of OC were independent risk factor of cerebral hemorrhage in women, it was infered history of pregnant hypertension probably increased the risk of cerebral hemorrhage by influencing blood pressure. No correlations between cerebral hemorrhage in women and history of menstruation and child bearing were found.
