CAJ | 학술논문

视网膜是体内代谢最旺盛的组织器官之一,氧需求量很高.视网膜长期处于低氧状态(如糖尿病眼病)会产生显著的、严重的不良后果,一般认为这是导致视网膜结构或功能不可逆性改变的根本原因.然而,采用传统方法测量视网膜氧张量有多方面的局限性.随着磁共振成像技术的发展,采用MRI进行无创地检测视网膜氧张量变化已成为可能.本文对糖尿病视网膜病变的MR研究进展进行综述.
시망막시체내대사최왕성적조직기관지일,양수구량흔고.시망막장기처우저양상태(여당뇨병안병)회산생현저적、엄중적불량후과,일반인위저시도치시망막결구혹공능불가역성개변적근본원인.연이,채용전통방법측량시망막양장량유다방면적국한성.수착자공진성상기술적발전,채용MRI진행무창지검측시망막양장량변화이성위가능.본문대당뇨병시망막병변적MR연구진전진행종술.
The function of the retina is sensitive to oxygen tension, and any changes in oxygen perfusion associated with retinal vessel diseases, such as diabetic retinopathy could affect inner retinal oxygen responses (ΔPO_2). However, the application of currently available techniques in measurements of the retinal oxygenation is limited. Recently, with the development of MRI, it is possible to detect ΔPO_2 noninvasively, and the effects are satisfactory. The application of MR based measurements of ΔPO_2 following the shift from breathing room air were reviewed in this article.