国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2012年
7期
496-500
,共5页
卒中%脑缺血%脑梗死%疲劳%认知障碍%抑郁症
卒中%腦缺血%腦梗死%疲勞%認知障礙%抑鬱癥
졸중%뇌결혈%뇌경사%피로%인지장애%억욱증
Stroke%Brain Ischemia%Brain Infarction%Fatigue%Cognition Disorders%Depression
目的 探讨腔隙性卒中后疲劳与认知障碍和抑郁的相关性.方法 纳入2009年9月至2010年11月期间住院的103例腔隙性卒中患者,采用疲劳量表-14(Fatigue Scale,FS-14)、疲劳严重程度量表(Fatigue Severity Scale,FSS-9)评价卒中后疲劳,简易精神状态检查量表(Mini-Mental State Examinat ion,MMSE)和蒙特利尔认知评估量表(Montreal Cognitive Assessment,MoCA)评价认知功能,抑郁自评量表(Self-Rating Depression Scale,SDS)和汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)评价抑郁情况.结果 通过不同量表评定,分别有34例(33.01％) (FSS-9)和45例(43.69％)(FS-14)存在疲劳.在根据FSS-9评分确定的34例疲劳患者中,有20例存在认知损害,26例存在抑郁,16例同时存在认知损害和抑郁.Pearson相关分析显示,FS-14评分与MMSE评分(r=-0.307,P =0.002)和MoCA评分(r=-0.457,P=0.000)呈显著负相关,而与SDS评分(r=0.368,P=0.000)和HAMD评分(r=0.526,P=0.000)呈显著正相关；FSS-9评分亦与MMSE评分(r=-0.292,P=0.003)和MoCA评分(r=-0.340,P=0.000)呈显著负相关,而与SDS评分(r=0.403,P=0.000)和HAMD评分(r=0.564,P=0.000)呈显著正相关.结论 腔隙性卒中患者的疲劳、认知损害和抑郁发生率均较高,疲劳与认知损害和抑郁之间存在一定的相关性.
目的 探討腔隙性卒中後疲勞與認知障礙和抑鬱的相關性.方法 納入2009年9月至2010年11月期間住院的103例腔隙性卒中患者,採用疲勞量錶-14(Fatigue Scale,FS-14)、疲勞嚴重程度量錶(Fatigue Severity Scale,FSS-9)評價卒中後疲勞,簡易精神狀態檢查量錶(Mini-Mental State Examinat ion,MMSE)和矇特利爾認知評估量錶(Montreal Cognitive Assessment,MoCA)評價認知功能,抑鬱自評量錶(Self-Rating Depression Scale,SDS)和漢密爾頓抑鬱量錶(Hamilton Depression Scale,HAMD)評價抑鬱情況.結果 通過不同量錶評定,分彆有34例(33.01％) (FSS-9)和45例(43.69％)(FS-14)存在疲勞.在根據FSS-9評分確定的34例疲勞患者中,有20例存在認知損害,26例存在抑鬱,16例同時存在認知損害和抑鬱.Pearson相關分析顯示,FS-14評分與MMSE評分(r=-0.307,P =0.002)和MoCA評分(r=-0.457,P=0.000)呈顯著負相關,而與SDS評分(r=0.368,P=0.000)和HAMD評分(r=0.526,P=0.000)呈顯著正相關；FSS-9評分亦與MMSE評分(r=-0.292,P=0.003)和MoCA評分(r=-0.340,P=0.000)呈顯著負相關,而與SDS評分(r=0.403,P=0.000)和HAMD評分(r=0.564,P=0.000)呈顯著正相關.結論 腔隙性卒中患者的疲勞、認知損害和抑鬱髮生率均較高,疲勞與認知損害和抑鬱之間存在一定的相關性.
목적 탐토강극성졸중후피로여인지장애화억욱적상관성.방법 납입2009년9월지2010년11월기간주원적103례강극성졸중환자,채용피로량표-14(Fatigue Scale,FS-14)、피로엄중정도량표(Fatigue Severity Scale,FSS-9)평개졸중후피로,간역정신상태검사량표(Mini-Mental State Examinat ion,MMSE)화몽특리이인지평고량표(Montreal Cognitive Assessment,MoCA)평개인지공능,억욱자평량표(Self-Rating Depression Scale,SDS)화한밀이돈억욱량표(Hamilton Depression Scale,HAMD)평개억욱정황.결과 통과불동량표평정,분별유34례(33.01％) (FSS-9)화45례(43.69％)(FS-14)존재피로.재근거FSS-9평분학정적34례피로환자중,유20례존재인지손해,26례존재억욱,16례동시존재인지손해화억욱.Pearson상관분석현시,FS-14평분여MMSE평분(r=-0.307,P =0.002)화MoCA평분(r=-0.457,P=0.000)정현저부상관,이여SDS평분(r=0.368,P=0.000)화HAMD평분(r=0.526,P=0.000)정현저정상관；FSS-9평분역여MMSE평분(r=-0.292,P=0.003)화MoCA평분(r=-0.340,P=0.000)정현저부상관,이여SDS평분(r=0.403,P=0.000)화HAMD평분(r=0.564,P=0.000)정현저정상관.결론 강극성졸중환자적피로、인지손해화억욱발생솔균교고,피로여인지손해화억욱지간존재일정적상관성.
Objective To investigate the correlation between fatigue and cognitive impairment and depression after lacunar stroke.Methods A total of 103 patients with lacunar infarction admitted from September 2009 to November 2010 were enrolled.Post-stroke fatigue was evaluated with the Fatigue Scale (FS-14) and the Fatigue Severity Scale (FSS-9); cognitive function was evaluated with the mini-mental state examination (MMSE) and the Montreal cognitive assessment (MoCA); and depression was evaluated with the self-rating depression scale (SDS) and the Hamilton Depression Rating Scale (HAMD).Results There were 34 patients (33.01％) (FSS-9) and 45 patients (43.69％) (FS-14) had fatigue.Of the 34 fatigue patients determined with FSS-9 scores,20 had cognitive impairment,26 had depression,and 16 had both cognitive impairment and depression.The Pearson correlation analysis showed that the FS-14 scores were siguificantly negatively correlated with the scores of MMSE (r =-0.307,P =0.002) and MoCA (r =-0.457,P=0.000),and significantly positively correlated with the scores of SDS (r =0.368,P =0.000) and HAMD (r =0.526,P =0.000); the FSS-9 scores were significantly negatively correlated with the scores of MMSE (r =-0.292,P=0.003) and MoCA (r=-0.340,P=0.000),and significantly positively correlated with the scores of SDS (r =0.403,P =0.000) and HAMD (r =0.564,P =0.000).Conclusions The incidence of fatigue,cognitive impairment and depression was higher.There was a certain correlation between fatigue and cognitive impairment and depression.
