食品与药品
食品與藥品
식품여약품
FOOD AND DRUG
2009年
3期
51-52
,共2页
赵长美%曲建全%郭风仙%穆淑娥%宋晓红
趙長美%麯建全%郭風仙%穆淑娥%宋曉紅
조장미%곡건전%곽풍선%목숙아%송효홍
透明质酸钠%溶血%pH值
透明質痠鈉%溶血%pH值
투명질산납%용혈%pH치
sodium hyaluronate%hemolysis%pH value
目的 探讨pH值对透明质酸钠(HA)溶液溶血性的影响.方法 调整0.4%HA溶液的pH值,以1%羊血悬浮液检测溶血性.结果 0.4%HA溶液的pH<4时,溶血检测阳性;调整pH 5.5～8.0时,溶血阴性.结论 0.4%HA溶液在pH<4时,其溶血性检测结果为假阳性.检测时应将HA溶液的pH调至5.5～8.0.
目的 探討pH值對透明質痠鈉(HA)溶液溶血性的影響.方法 調整0.4%HA溶液的pH值,以1%羊血懸浮液檢測溶血性.結果 0.4%HA溶液的pH<4時,溶血檢測暘性;調整pH 5.5～8.0時,溶血陰性.結論 0.4%HA溶液在pH<4時,其溶血性檢測結果為假暘性.檢測時應將HA溶液的pH調至5.5～8.0.
목적 탐토pH치대투명질산납(HA)용액용혈성적영향.방법 조정0.4%HA용액적pH치,이1%양혈현부액검측용혈성.결과 0.4%HA용액적pH<4시,용혈검측양성;조정pH 5.5～8.0시,용혈음성.결론 0.4%HA용액재pH<4시,기용혈성검측결과위가양성.검측시응장HA용액적pH조지5.5～8.0.
Objective To study the effect of pH on the hemolysis test of sodium hyaluronate solution. Methods The hemolysis test was performed with 1% suspension of sheep blood to be added into 0.4 % sodium hyaluronate solution of different pH values. Results When the pH value is less than 4, the hemolysis test is positive; when adjusting the pH value to 5.5～8.0, the hemolysis test is negative. Conclusion When the pH value of 0.4 % sodium hyahronate solution is less than 4, the false positive result of hemolysis test has no relationship with the solution itself. The hemolysis test shall be performed with the pH value in the range of 5.5～8.0.
