CAJ | 학술논문

目的评价体外循环搏动灌注对肾功能不全患者的影响.方法 2007年1月至2010年5月共收治肾功能不全患者55例行心脏直视手术,随机分为搏动灌注组(P组)28例与非搏动灌注组(NP组)27例.分别检测两组患者术前及术后24 h尿素氮、肌酐、尿酸、术中单位时间尿量.主动脉开放前进行血气、电解质分析及乳酸测定.结果主动脉开放前P组乳酸值明显低于NP组(P＜0.01),手术前后尿酸差值P组明显高于NP组(P＜0.01),术中单位时间尿量P组明显多于NP组(P＜0.01).结论与非搏动灌注相比,体外循坏采用搏动灌注有利于肾功能不全患者的肾保护.
목적 평개체외순배박동관주대신공능불전환자적영향.방법 2007년1월지2010년5월공수치신공능불전환자55례행심장직시수술,수궤분위박동관주조(P조)28례여비박동관주조(NP조)27례.분별검측량조환자술전급술후24 h뇨소담、기항、뇨산、술중단위시간뇨량.주동맥개방전진행혈기、전해질분석급유산측정.결과 주동맥개방전P조유산치명현저우NP조(P＜0.01),수술전후뇨산차치P조명현고우NP조(P＜0.01),술중단위시간뇨량P조명현다우NP조(P＜0.01).결론 여비박동관주상비,체외순배채용박동관주유리우신공능불전환자적신보호.
Objective To evaluate the clinical effects of pulsatile perfusion on the renal inadequacy during cardiopulmonary bypass ( CPB). Methods From January 2007 to May 2010, 55 patients with renal inadequacy undergoing open heart surgery were randomized into pulsatile group ( n = 28 ) and nonpulsatile group (n =27). Following parameters were examined: urea nitrogen , creatinine,uric acid, urine volume and blood gas, electrolyte and lactic acid before arteriae aorta opening. Results The urine volume during CPB was significant higher in the pulsatile group ( P ＜0. 01). The blood lactate level before arteriae aorta opening were significant lower in the pulsatile group ( P ＜0. 01). Conclusion The pulsatile flow is better than nopulsatile flow in oxygen metabolism of renal protection.