CAJ | 학술논문

目的通过对39例头孢唑肟钠注射剂引起的不良反应报告进行分析,探讨头孢唑肟钠注射剂不良反应发生的规律和临床表现,提示临床注意监测其不良反应,避免严重后果.方法对39例头孢唑肟钠注射剂引起的不良反应进行统计和分析.结果女22例,男17例,女性多于男性;患者年龄在0～50岁之间,其中10岁以下儿童发生率最高,为46.15%;静脉滴注给药38例(97.44%),肌内注射给药1例(2.56%);头孢唑肟钠注射剂的主要不良反应是过敏反应(66.67%),此外还可引起过敏性休克、呼吸系统损害等较少见的、严重的不良反应.结论要合理使用头孢唑肟钠注射剂,避免和减少不良反应的发生.
목적 통과대39례두포서우납주사제인기적불량반응보고진행분석,탐토두포서우납주사제불량반응발생적규률화림상표현,제시림상주의감측기불량반응,피면엄중후과.방법 대39례두포서우납주사제인기적불량반응진행통계화분석.결과 녀22례,남17례,녀성다우남성;환자년령재0～50세지간,기중10세이하인동발생솔최고,위46.15%;정맥적주급약38례(97.44%),기내주사급약1례(2.56%);두포서우납주사제적주요불량반응시과민반응(66.67%),차외환가인기과민성휴극、호흡계통손해등교소견적、엄중적불량반응.결론 요합리사용두포서우납주사제,피면화감소불량반응적발생.
Objective To explore the incidence and clinical manifestations of ceftizoxime sodium-associated adverse reactions by analyzing the reports of adverse reactions caused by 39 cases of ceftizoxime sodium injections, this thesis aims at exploring the law of adverse reactions and of ceftizoxime sodium injection, reminding clinical treatment to monitor the adverse reactions to avoid serious consequences.Methods The adverse reactions caused by ceftizoxime sodium injections in 39 patients were analyzed statisticcally. Results More adverse reactions occurred in females than in males( 22 vs 17 ). The patients was 0 to 50 years old, mostly children younger than 10 ( 46.15% ). 38 patients ( 97.44% ) were due to intravenous drip and one ( 2.56% ) due to tointramuscular injection. The main adverse reaction was allergic reaction(66.67% ) in addition, other rare and severe adverse reactions including anaphylactic shock and respiratory damage could developed. Conclusions Ceftizoxime sodium injections should be rationally used to avoid or reduce the incidence of adverse reactions.