CAJ | 학술논문

目的探讨大光斑低能量调Q开关Nd:YAG 1064 nm激光治疗黄褐斑的疗效和安全性.方法对45例黄褐斑患者,使用大光斑低能量调Q开关Nd:YAG 1064 nm激光治疗,每周1次,每例患者治疗11～20次,分别于治疗前、治疗5周、10周以及治疗完成时,进行患者自评疗效、医师评价以及皮肤多功能测试仪检测皮肤黑素指数和经皮水分丢失评价.结果黄褐斑皮损区激光治疗5周、10周、完成时黑素指数较治疗前均有显著性减少,正常皮肤区治疗前后无差异;治疗5次、10次和完成时经皮水分较治疗前均有显著性增高,治疗后患者的皮肤光滑、细腻、毛孔缩小、更有弹性.治疗效果评价:基本治愈8例(17.78％),显效25例(55.56％),好转11例(24.44％),无效1例(2 22％),有效率为73.33％.结论大光斑低能量调Q开关1064 nm激光治疗黄褐斑疗效确切,副作用小,安全性高.
목적 탐토대광반저능량조Q개관Nd:YAG 1064 nm격광치료황갈반적료효화안전성.방법 대45례황갈반환자,사용대광반저능량조Q개관Nd:YAG 1064 nm격광치료,매주1차,매례환자치료11～20차,분별우치료전、치료5주、10주이급치료완성시,진행환자자평료효、의사평개이급피부다공능측시의검측피부흑소지수화경피수분주실평개.결과 황갈반피손구격광치료5주、10주、완성시흑소지수교치료전균유현저성감소,정상피부구치료전후무차이;치료5차、10차화완성시경피수분교치료전균유현저성증고,치료후환자적피부광활、세니、모공축소、경유탄성.치료효과평개:기본치유8례(17.78％),현효25례(55.56％),호전11례(24.44％),무효1례(2 22％),유효솔위73.33％.결론 대광반저능량조Q개관1064 nm격광치료황갈반료효학절,부작용소,안전성고.
Objective To clarify the effectiveness of QS Nd ∶ YAG laser on melasma in Chinese patients.Methods A group (n=45) of patients previously diagnosed as facial melasma were treated with QS Nd ∶ YAG laser at approximately 1 week intervals.Eleven to twenty treatments were per formed for each patient.The treatment efficacy of QS Nd ∶ YAG laser was evaluated by patients and doctors,respectively,at various time point such as before treatment,5 weeks and 10 weeks after treatment and end of the treatment.The skin melanin index and the transepidermal water loss were e valuated by the skin multifunction tester at different time point,respectively.Results Compared with untreated,the melanin index of melasma areas decreased significantly after the laser treatment for 5 weeks,10 weeks and the end of treatment.But there was no significant difference in the melanin index of normal skin areas with or without laser treatment.Compared with untreated,the transpidermal water loss of melasma areas increased significantly after the laser treatment for 5 weeks,10 weeks and end of treatment.The patients' skin became smooth,delicate,pores shrink and more flexible.In 45 melasma patients treated by QS Nd ∶ YAG laser,8 cases basically cured (17.78 ％),25 cases were markedly effective (55.56 ％),12 cases improved (24.44 ％) and only 1 case was uneffective (2.22 ％).Theoverall effective rate was 73.33 ％.Conclnsions QSNd∶ YAG laser is a useful treatment modality for Chinese women who have melasma with precise efficacy,less side effects and high safety.