中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2010年
4期
22-23
,共2页
董加建%张金盈%李蕾%王魁风%陈坡%杨培灵
董加建%張金盈%李蕾%王魁風%陳坡%楊培靈
동가건%장금영%리뢰%왕괴풍%진파%양배령
血管紧张素Ⅱ%胰岛素抵抗%左室重构
血管緊張素Ⅱ%胰島素牴抗%左室重構
혈관긴장소Ⅱ%이도소저항%좌실중구
Angiotensin Ⅱ%Insulin resistance%Left ventricular remodeling
目的 探讨原发性高血压(EH)患者胰岛素抵抗与血管紧张素Ⅱ(AngⅡ)、左室重构的相关性.方法 收集120例EH患者,根据HOMA-IR公式计算的胰岛素抵抗指数将其分为两组:胰岛素抵抗组(IR)、非胰岛素抵抗组(N-IR),测量并比较两组间电解质、血脂、血肌酐清除率、AngⅡ、左室射血分数、左室质量指数(LVMI)水平.结果 LVMI、AngⅡ水平IR组均明显高于N-IR组(P＜0.05).结论 EH患者胰岛素抵抗与血AngⅡ水平有关,并可能与左室重构有关.
目的 探討原髮性高血壓(EH)患者胰島素牴抗與血管緊張素Ⅱ(AngⅡ)、左室重構的相關性.方法 收集120例EH患者,根據HOMA-IR公式計算的胰島素牴抗指數將其分為兩組:胰島素牴抗組(IR)、非胰島素牴抗組(N-IR),測量併比較兩組間電解質、血脂、血肌酐清除率、AngⅡ、左室射血分數、左室質量指數(LVMI)水平.結果 LVMI、AngⅡ水平IR組均明顯高于N-IR組(P＜0.05).結論 EH患者胰島素牴抗與血AngⅡ水平有關,併可能與左室重構有關.
목적 탐토원발성고혈압(EH)환자이도소저항여혈관긴장소Ⅱ(AngⅡ)、좌실중구적상관성.방법 수집120례EH환자,근거HOMA-IR공식계산적이도소저항지수장기분위량조:이도소저항조(IR)、비이도소저항조(N-IR),측량병비교량조간전해질、혈지、혈기항청제솔、AngⅡ、좌실사혈분수、좌실질량지수(LVMI)수평.결과 LVMI、AngⅡ수평IR조균명현고우N-IR조(P＜0.05).결론 EH환자이도소저항여혈AngⅡ수평유관,병가능여좌실중구유관.
Objective To investigate the relationship between insulin resistance and angiotensin Ⅱ , the left ventricular remodeling in patients with essential hypertension(EH). Methods According to the insulin resistance index, 120 cases of EH were divided into two groups: insulin resistance group (IR), non- insulin resistant group (N-IR). And the electrolyte, blood lipids, creatinine clearance rate, Ang Ⅱ , left ventricular ejection fraction and left ventricular mass index (LVMI) were measured and the results were compared between the two groups. Results LVMI and Ang Ⅱ levels of IR group were significantly higher than those of N - IR group ( P ＜ 0.05). Conclusions Insulin resistance is related with the levels of Ang Ⅱ , and may be related with left ventricular remodeling.
