中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2009年
3期
206-209
,共4页
刘春灵%曹晋桂%周平%徐华%纪树国%李衍波%张俊红%刘晓宇%郑春茜
劉春靈%曹晉桂%週平%徐華%紀樹國%李衍波%張俊紅%劉曉宇%鄭春茜
류춘령%조진계%주평%서화%기수국%리연파%장준홍%류효우%정춘천
支原体,肺炎%疾病暴发流行%日托幼儿园%通风
支原體,肺炎%疾病暴髮流行%日託幼兒園%通風
지원체,폐염%질병폭발류행%일탁유인완%통풍
Mycoplasma pneumoniae%Disease outbreaks%Child day care centers%Ventilation
目的 分析北京市某所幼儿园的1个班级2006年7月暴发的一起肺炎支原体肺炎(MPP)的流行病学和临床特点.方法 调查该幼儿园环境,查阅2005年8月1日-2006年7月31日间的幼儿园考勤记录,面对面或电话方式向因病缺勤的儿童家长调查儿童患病情况.住院患儿病史资料专人表格化采集,结合其住院资料进行临床分析.采用日本Fujirebio公司生产的血清Serodia-Myco Ⅱ凝集试验试剂盒检测MP-IgM抗体.结果 2006年7月中旬,该所幼儿园有大、中、小3个班级,大班的25名6岁儿童中,4 d内3例患肺炎先后住院,均诊断为MPP.在2006年5月下旬至7月中旬,大班共8例儿童发热、咳嗽,5例做了X线检查,均诊断是肺炎,MP抗体检测均阳性,其中3例双份血清MP抗体滴度升高4倍以上.此间,幼儿园的其他2个班级的儿童无人患肺炎,5例肺炎儿童的家长和大班的教师也无患肺炎者.大班教室通风及日照差,是2006年3月因故临时搬迁至此.有效改善教室通风后,至2006年9月初,大班儿童中未再出现新的肺炎病例.5名肺炎患儿均无鼻塞、流涕,也无耳痛、皮疹等症状及其他肺外并发症,外周血WBC总数均不高[(3.9～7.7)×109].结论这是一起发生在幼儿园的MPP局部暴发,教室通风不良是导致MPP暴发的主要原因.儿童MP感染更易导致肺炎.
目的 分析北京市某所幼兒園的1箇班級2006年7月暴髮的一起肺炎支原體肺炎(MPP)的流行病學和臨床特點.方法 調查該幼兒園環境,查閱2005年8月1日-2006年7月31日間的幼兒園攷勤記錄,麵對麵或電話方式嚮因病缺勤的兒童傢長調查兒童患病情況.住院患兒病史資料專人錶格化採集,結閤其住院資料進行臨床分析.採用日本Fujirebio公司生產的血清Serodia-Myco Ⅱ凝集試驗試劑盒檢測MP-IgM抗體.結果 2006年7月中旬,該所幼兒園有大、中、小3箇班級,大班的25名6歲兒童中,4 d內3例患肺炎先後住院,均診斷為MPP.在2006年5月下旬至7月中旬,大班共8例兒童髮熱、咳嗽,5例做瞭X線檢查,均診斷是肺炎,MP抗體檢測均暘性,其中3例雙份血清MP抗體滴度升高4倍以上.此間,幼兒園的其他2箇班級的兒童無人患肺炎,5例肺炎兒童的傢長和大班的教師也無患肺炎者.大班教室通風及日照差,是2006年3月因故臨時搬遷至此.有效改善教室通風後,至2006年9月初,大班兒童中未再齣現新的肺炎病例.5名肺炎患兒均無鼻塞、流涕,也無耳痛、皮疹等癥狀及其他肺外併髮癥,外週血WBC總數均不高[(3.9～7.7)×109].結論這是一起髮生在幼兒園的MPP跼部暴髮,教室通風不良是導緻MPP暴髮的主要原因.兒童MP感染更易導緻肺炎.
목적 분석북경시모소유인완적1개반급2006년7월폭발적일기폐염지원체폐염(MPP)적류행병학화림상특점.방법 조사해유인완배경,사열2005년8월1일-2006년7월31일간적유인완고근기록,면대면혹전화방식향인병결근적인동가장조사인동환병정황.주원환인병사자료전인표격화채집,결합기주원자료진행림상분석.채용일본Fujirebio공사생산적혈청Serodia-Myco Ⅱ응집시험시제합검측MP-IgM항체.결과 2006년7월중순,해소유인완유대、중、소3개반급,대반적25명6세인동중,4 d내3례환폐염선후주원,균진단위MPP.재2006년5월하순지7월중순,대반공8례인동발열、해수,5례주료X선검사,균진단시폐염,MP항체검측균양성,기중3례쌍빈혈청MP항체적도승고4배이상.차간,유인완적기타2개반급적인동무인환폐염,5례폐염인동적가장화대반적교사야무환폐염자.대반교실통풍급일조차,시2006년3월인고림시반천지차.유효개선교실통풍후,지2006년9월초,대반인동중미재출현신적폐염병례.5명폐염환인균무비새、류체,야무이통、피진등증상급기타폐외병발증,외주혈WBC총수균불고[(3.9～7.7)×109].결론저시일기발생재유인완적MPP국부폭발,교실통풍불량시도치MPP폭발적주요원인.인동MP감염경역도치폐염.
Objective To study the epidemiological and clinical features of the mycoplasma pneumoniae pneumonia (MPP) that occurred in a single class of a kindergarten in Beijing in July 2006. Methods The environment and the attendance record of the kindergarten from the beginning of August 2005 to the end of July 2006 were investigated, and the sick status of the children absent for illness were interviewed by face to face or telephone through their parents. The disease data of the in-patient children with MPP were collected throughquestionnaires and analyzed. Serological screeningfor MP was performed with the Serodia Myco Ⅱ gelatin particle agglutination test (Fujirebio,Japan). Results In mid-July 2006 ,in a day-care kindergarten with 3 grade classes,3 out of 25 six-year-old children in the top class were hospitalized within 4 days and diagnosed as MPP. A total of 8 children had the symptoms of fever and cough during late May and mid-July in 2006,5 children conduct chest radiographs and all had pneumonia, all these five children showed antibody positive for MP,3 of them showed a more than 4-fold increase in antibody titer to MP in serum. There were no pneumoniae cases in the other two classes during the same period, and no pneumoniae cases happened among the teachers in the top class and the parents of the 5 pneumoniae children. All the children were moved to this classroom temporarily with limited ventilation and sunshine in March 2006. After improvement of the ventilation in the classroom, no additional pneumoniae cases occurred in the top class till the early September 2006. The 5 MPP children showed neither sneeze and nasal obstruction,nor skin rash, earache and any other extrapulmonary complication, and their peripheral white blood cell count was in the normal range (3.9 - 7.7)×109. Conclusion The MPP outbreak in a kindergarten was caused byed poor ventilation of the temporary classroom. MP infection in children is liable to cause pneumonia.
