CAJ | 학술논문

目的探讨儿童慢性粒细胞白血病(CML)的临床、实验室特点及其治疗.方法回顾性分析1994年12月至2009年10月收治的12例CML患儿临床及实验室资料.结果 CML多见于5～9岁的患儿,男女之比为5∶1.出现症状或体征至明确诊断的时间为3 d～1年.常见症状为发热、出血、乏力;部分因体检发现血象异常或脾大而就诊.白细胞及血小板数量明显增多.结论 CML小儿少见,症状不典型,其白细胞数与成年人相比有显著差别.
목적 탐토인동만성립세포백혈병(CML)적림상、실험실특점급기치료.방법 회고성분석1994년12월지2009년10월수치적12례CML환인림상급실험실자료.결과 CML다견우5～9세적환인,남녀지비위5∶1.출현증상혹체정지명학진단적시간위3 d～1년.상견증상위발열、출혈、핍력;부분인체검발현혈상이상혹비대이취진.백세포급혈소판수량명현증다.결론 CML소인소견,증상불전형,기백세포수여성년인상비유현저차별.
Objective To study the clinical and laboratory characteristics and treatments in children with chronic myelogenous leukemia (CML). Methods Respective analyze of the clinical and laboratory data of twelve pediatric patients with CML from December 1994 to October 2009 was performed. Results The disease predominately affected children from 5 to 9 years old (50 % of the patients), with a higher prevalence in boys than girls (gender ratio: 5:1). The duration before the diagnosis was different from three days to one year. The main presenting symptoms were fever, bleeding,asthenia, and complaints related to splenomegaly.Some cases were diagnosed incidentally. Markedly raised leukocyte and platelet counts were common.Conclusion CML in children is rare, and average level of WBC count seems to be much higher than adult.