中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2011年
8期
786-788
,共3页
韦所苏%邹云锋%徐永芳%刘金纪%农全兴%白玉%石艺%钟晓妮%黄文祥%梁浩%黄爱龙
韋所囌%鄒雲鋒%徐永芳%劉金紀%農全興%白玉%石藝%鐘曉妮%黃文祥%樑浩%黃愛龍
위소소%추운봉%서영방%류금기%농전흥%백옥%석예%종효니%황문상%량호%황애룡
艾滋病病毒%男男性行为者%暴露前预防%接受意愿
艾滋病病毒%男男性行為者%暴露前預防%接受意願
애자병병독%남남성행위자%폭로전예방%접수의원
Human immunodeficiency virus%Men who have sex with men%Pre-exposure prophylaxis%Acceptability
目的 了解广西地区男男性行为者(MSM)对暴露前预防(PrEP)HIV感染的接受意愿及其影响因素.方法 采用滚雪球法招募650名MSM,利用自行设计的调查问卷一对一面访,了解MSM与艾滋病相关的高危行为、对PrEP的知晓情况及接受意愿.结果 假设PrEP使用的药物安全、有效且免费提供,有91.9%的MSM表示愿意服用药物.自述愿意服药的原因主要为可降低HⅣ感染的风险,不愿意服用药物的原因主要为担心药物的副作用和怀疑药物的效果.logistic回归分析显示,与接受PrEP意愿有关的因素为"是否通过朋友介绍性伴"(OR=6.21,P=0.020)、"是否有能力预防HIV感染"(OR=O.32,P=0.010)、"是否拒绝与不使用安全套的人发生性行为"(OR=0.34,P=0.010)、"是否建议朋友接受PrEP"(OR=39.32,P=0.000).结论 药物的安全性、有效性及费用可能是影响广西地区MSM接受PrEP的主要因素,免费提供安全、有效且副作用小的药物可能是推广PrEP的较好方式;以同伴教育的方式宣传PrEP可能会提高其接受意愿.
目的 瞭解廣西地區男男性行為者(MSM)對暴露前預防(PrEP)HIV感染的接受意願及其影響因素.方法 採用滾雪毬法招募650名MSM,利用自行設計的調查問捲一對一麵訪,瞭解MSM與艾滋病相關的高危行為、對PrEP的知曉情況及接受意願.結果 假設PrEP使用的藥物安全、有效且免費提供,有91.9%的MSM錶示願意服用藥物.自述願意服藥的原因主要為可降低HⅣ感染的風險,不願意服用藥物的原因主要為擔心藥物的副作用和懷疑藥物的效果.logistic迴歸分析顯示,與接受PrEP意願有關的因素為"是否通過朋友介紹性伴"(OR=6.21,P=0.020)、"是否有能力預防HIV感染"(OR=O.32,P=0.010)、"是否拒絕與不使用安全套的人髮生性行為"(OR=0.34,P=0.010)、"是否建議朋友接受PrEP"(OR=39.32,P=0.000).結論 藥物的安全性、有效性及費用可能是影響廣西地區MSM接受PrEP的主要因素,免費提供安全、有效且副作用小的藥物可能是推廣PrEP的較好方式;以同伴教育的方式宣傳PrEP可能會提高其接受意願.
목적 료해엄서지구남남성행위자(MSM)대폭로전예방(PrEP)HIV감염적접수의원급기영향인소.방법 채용곤설구법초모650명MSM,이용자행설계적조사문권일대일면방,료해MSM여애자병상관적고위행위、대PrEP적지효정황급접수의원.결과 가설PrEP사용적약물안전、유효차면비제공,유91.9%적MSM표시원의복용약물.자술원의복약적원인주요위가강저HⅣ감염적풍험,불원의복용약물적원인주요위담심약물적부작용화부의약물적효과.logistic회귀분석현시,여접수PrEP의원유관적인소위"시부통과붕우개소성반"(OR=6.21,P=0.020)、"시부유능력예방HIV감염"(OR=O.32,P=0.010)、"시부거절여불사용안전투적인발생성행위"(OR=0.34,P=0.010)、"시부건의붕우접수PrEP"(OR=39.32,P=0.000).결론 약물적안전성、유효성급비용가능시영향엄서지구MSM접수PrEP적주요인소,면비제공안전、유효차부작용소적약물가능시추엄PrEP적교호방식;이동반교육적방식선전PrEP가능회제고기접수의원.
Objective To study the acceptability of pre-exposure prophylaxis (PrEP) to prevent the transmission of HIV among men who have sex with men (MSM) in Guangxi, China.Methods Snow-balling methods were used to recruit 650 MSM in Guangxi. Questionnaires and interview were administrated to these 650 men, using a self-designed questionnaire and face to face interviews to collect information on HIV-related risk behaviors, knowledge and acceptability of PrEP.effective, safe and free of charge', 597 (91.9%) of the 650 MSM claimed that they would accept it,who refused to use it, most of them said that were afraid of the side-effect and doubted on the effectiveness of PrEP. Data from logistic regression analysis showed that those who had found partners through friends (OR=6.21, P=0.020) and those who would advise his friend to use PrEP (OR=39.32, P=0.000) were more likely to accept PrEP. Those who thought they could protect themselves from HIV infection (OR=0.32, P=0.010) or not having sex with the ones who refused to use a condom (OR=0.34, P=0.010) were less likely to accept PrEP. Conclusion Effectiveness, safety and cost seemed to be the main influential factors related to the acceptability of PrEP. Peer education might improve the acceptability of PrEP.
