国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2009年
23期
20-22
,共3页
急性脑梗死%脑钠肽%脑钠肽前体N-末端肽%C-反应蛋白
急性腦梗死%腦鈉肽%腦鈉肽前體N-末耑肽%C-反應蛋白
급성뇌경사%뇌납태%뇌납태전체N-말단태%C-반응단백
Acute cerebral infarction%Brain natriuretic peptide(BNP)%N-terminal probrain natriuretic peptide(NTBNP)%C-reactive protein(CRP)
目的 探讨血浆脑钠肽前体(NTBNP)与C-反应蛋白(CRP)在脑梗死中的表达及其临床意义.方法 应用酶联免疫分析法测定40例脑梗死急性期患者和40例亚急期患者血浆NTBNP与CRP浓度,并以30例健康自愿体检者作对照.结果 脑梗死组急性期血浆NTBNP、CRP含量显著高于亚急性期(P<0.01),且两者与正常埘照组相比,差异有极显著性(P<0.01),大面积脑梗夕匕组血浆BNP、CRP含最显著高于非大面积脑梗死组(P<0.01).结论 脑梗死患者急性期血浆NTBNP和CRP水平明显升高,提示二者在脑梗死的发病过程中起重要作用.
目的 探討血漿腦鈉肽前體(NTBNP)與C-反應蛋白(CRP)在腦梗死中的錶達及其臨床意義.方法 應用酶聯免疫分析法測定40例腦梗死急性期患者和40例亞急期患者血漿NTBNP與CRP濃度,併以30例健康自願體檢者作對照.結果 腦梗死組急性期血漿NTBNP、CRP含量顯著高于亞急性期(P<0.01),且兩者與正常塒照組相比,差異有極顯著性(P<0.01),大麵積腦梗夕匕組血漿BNP、CRP含最顯著高于非大麵積腦梗死組(P<0.01).結論 腦梗死患者急性期血漿NTBNP和CRP水平明顯升高,提示二者在腦梗死的髮病過程中起重要作用.
목적 탐토혈장뇌납태전체(NTBNP)여C-반응단백(CRP)재뇌경사중적표체급기림상의의.방법 응용매련면역분석법측정40례뇌경사급성기환자화40례아급기환자혈장NTBNP여CRP농도,병이30례건강자원체검자작대조.결과 뇌경사조급성기혈장NTBNP、CRP함량현저고우아급성기(P<0.01),차량자여정상시조조상비,차이유겁현저성(P<0.01),대면적뇌경석비조혈장BNP、CRP함최현저고우비대면적뇌경사조(P<0.01).결론 뇌경사환자급성기혈장NTBNP화CRP수평명현승고,제시이자재뇌경사적발병과정중기중요작용.
Objective To explore the changes of plasma levels of NTBNP and CRP in patients with acute cerebral infarction and its possible pathophysiologic implications.Method* The level of plasma NTBNP and CRP of 40 patients with acute cerebral infarction,40 patients with subacute cerebral infarction and 30 healthy controls were determined by ELISA.Results The levels of NTBNP and CRP of patients with acute cerebral infarction were significantly higher than those in control and subacute cerebral infarction groups(P<0.01), and the plasma of NTBNP and CRP in patients with large area of infarction were significantly higher than those in patients with small area of infarction(P<0.01).Conclusions Plasma NTBNP and CRP are increased significantly in patients with cerebral infarction,they possibly play the most important key role in the pathogenesis of cerebral infarction.
