CAJ | 학술논문

目的观察雷米芬太尼复合丙泊酚麻醉用于老年患者腹腔镜胆囊切除术的应激反应的抑制作用.方法择期行腹腔镜胆囊切除术老年患者60例随机均分为两组.观察组用雷米芬太尼复合丙泊酚,对照组用芬太尼复合丙泊酚.记录麻醉诱导前(T_1)、插管前(T_2)、插管后30 min(T_3)、气腹毕(T_4)和术毕(T_5)的MAP、HR.检测T_1、T_3及术后2 h(T_6)血糖、胰岛素及血清皮质醇.结果对照组在T_2、T_3时MAP较T_1时下降、HR减慢(P<0.05),T_3、T_6时对照组血清皮质醇及血糖均高于T_1时且高于观察组(P<0.05).结论雷米芬太尼复合丙泊酚麻醉能有效抑制老年腹腔镜月日囊切除术患者应激反应.
목적 관찰뢰미분태니복합병박분마취용우노년환자복강경담낭절제술적응격반응적억제작용.방법 택기행복강경담낭절제술노년환자60례수궤균분위량조.관찰조용뢰미분태니복합병박분,대조조용분태니복합병박분.기록마취유도전(T_1)、삽관전(T_2)、삽관후30 min(T_3)、기복필(T_4)화술필(T_5)적MAP、HR.검측T_1、T_3급술후2 h(T_6)혈당、이도소급혈청피질순.결과 대조조재T_2、T_3시MAP교T_1시하강、HR감만(P<0.05),T_3、T_6시대조조혈청피질순급혈당균고우T_1시차고우관찰조(P<0.05).결론 뢰미분태니복합병박분마취능유효억제노년복강경월일낭절제술환자응격반응.
Objective To observe the inhibition of remifentanil combined with propofol on stress response in elderly patients undergoing laparoscopic cholecystectomy(LC). Methods Sixty old LC patients were divided randomly into two groups of observation group and control group with 30 eases each. Anesthesia with remifentanil and propofol was used in group observation group and fentanyl and propofol in group control group. MAP and HR were recorded before anesthesia(T_1), before intubatton(T_2) ,at 30 min after intubatton(T_3), the end of pneumoperitoneum(T_4) and the end of operation(T_5). Cortisol, insulin and blood sugar were measured at T_1, T_3 and 2 h (T_6) after operation. Results Compared to control group, MAP, HR, cortisol, insulin and blood sugar in observation group were not changed greatly at all time points. Conclusion Remifentanil combined with propofol anesthesia inhibits stress response to surgery more effective than fentanyl combined with propofol for elderly patients undergoing LC.