CAJ | 학술논문

目的研究血清C反应蛋白(CRP)及糖蛋白KL-6在手足口病并发神经源性肺水肿患儿中的含量变化隋况,并探讨相关护理措施,为手足口病并发神经源性肺水肿的诊断提供依据.方法随机选取2010年1月至2011年6月我院收治的96例手足口病并发神经源性肺水肿患儿,其中56例为重型患儿(重型组),40例为普通型患儿(普通组),另外随机选取同期年龄相仿的48例健康儿童(健康组),采用比浊法测定3组儿童的血清CRP含量,采用Elisa法测定糖蛋白KL-6的含量,对所测结果进行比较分析,总结手足口病的相关护理措施.结果比浊法测定检测CRP的结果显示,重型手足口病并发神经源性肺水肿患儿的CRP含量最高,普通型次之,健康组正常.Elisa法测定糖蛋白KL-6的结果显示,重型手足口病并发神经源性肺水肿患儿含量最高,普通型次之,健康组正常.数据分析发现3组儿童的上述2种指标的检测结果差异均有统计学意义.结论通过比较分析发现CRP及糖蛋白KL-6的含量与手足口病并发神经源性肺水肿的严重程度呈正相关,这2项可以作为临床判断该病严重程度的指标,合理的护理措施对患儿的康复非常重要.
목적 연구혈청C반응단백(CRP)급당단백KL-6재수족구병병발신경원성폐수종환인중적함량변화수황,병탐토상관호리조시,위수족구병병발신경원성폐수종적진단제공의거.방법 수궤선취2010년1월지2011년6월아원수치적96례수족구병병발신경원성폐수종환인,기중56례위중형환인(중형조),40례위보통형환인(보통조),령외수궤선취동기년령상방적48례건강인동(건강조),채용비탁법측정3조인동적혈청CRP함량,채용Elisa법측정당단백KL-6적함량,대소측결과진행비교분석,총결수족구병적상관호리조시.결과 비탁법측정검측CRP적결과현시,중형수족구병병발신경원성폐수종환인적CRP함량최고,보통형차지,건강조정상.Elisa법측정당단백KL-6적결과현시,중형수족구병병발신경원성폐수종환인함량최고,보통형차지,건강조정상.수거분석발현3조인동적상술2충지표적검측결과차이균유통계학의의.결론 통과비교분석발현CRP급당단백KL-6적함량여수족구병병발신경원성폐수종적엄중정도정정상관,저2항가이작위림상판단해병엄중정도적지표,합리적호리조시대환인적강복비상중요.
Objective To discuss the content of serum C-reactive protein and the glycoprotein KL- 6 in hand-foot and mouth disease complicated with neurogenic pulmonary edema children,and discuss related nursing measures,in order to provide the basis for diagnosis of hand-foot and mouth disease complicated with neurogenic pulmonary edema. Methods 96 cases of children patients with hand- foot and mouth disease complicated with neurogenic pulmonary edema from January 2010 to June 2011 were selected at random in our hospital,56 cases were heavy patients,40 patients were common type.Another 48 cases were randomly selected healthy volunteers.Using the turbidity to determine the content of C-reactive protein in serum,the Elisa method to determine the content of glycoprotein KL-6.The results were compared and the related nursing measures were summarized. Results The results of the turbidity for C-reactive protein showed that heavy patients were with the highest levels of CRP,common type followed subsequently,while the healthy group was normal.The results of Elisa for glycoprotein KL-6 showed that heavy patients were with the highest levels of glycoprotein KL-6,Common type followed subsequently,the healthy group was normal.By data analysis,we found that the two kinds of test results between three groups were obviously different. Conclusions Through comparative analysis,we found that the content of C- reactive protein and the glycoprotein KL-6 were positively correlated with the order of severity of hand-foot and mouth disease complicated with neurogenic pulmonary edema,which can be used as index of clinical judgment of the severity of the disease.Reasonable care measures are very impartant for recovery of the patients.