CAJ | 학술논문

对于邻位、间位取代苯胺与丙烯腈发生单氰乙基反应生成相应的N-氰乙基邻位取代苯胺和N-氰乙基间位取代苯胺的过程,AlCl_3具有高的催化活性.在芳香胺/丙烯腈/AlCl_3=1/1.10/(0.05～0.10)(摩尔比)、反应温度60～80℃,反应时间6～10 h的条件下,反应的收率达87%～90%.用毛细管气相色谱法分析了单氰乙基化反应中各组份的含量;所合成的7种N-氰乙基邻位取代苯胺和N-氰乙基间位取代苯胺用DTA-TG、UV、IR、~1H NMR和EA进行了物性和结构表征.
대우린위、간위취대분알여병희정발생단청을기반응생성상응적N-청을기린위취대분알화N-청을기간위취대분알적과정,AlCl_3구유고적최화활성.재방향알/병희정/AlCl_3=1/1.10/(0.05～0.10)(마이비)、반응온도60～80℃,반응시간6～10 h적조건하,반응적수솔체87%～90%.용모세관기상색보법분석료단청을기화반응중각조빈적함량;소합성적7충N-청을기린위취대분알화N-청을기간위취대분알용DTA-TG、UV、IR、~1H NMR화EA진행료물성화결구표정.
Mono-cyanoethylation addition reactions of o-substituted or m-substituted anilines with acrylonitrile have been carried out in the presence of AlCl_3 , resulting in N-β-cyanoethyl-α-substituted anilines, N-β-cyanoethyl-m-substituted anilines in high yield. Under the conditions of mole ratio of the reactants as substituted anilines: acrylonitrile: AlCl_3 = 1 : 1.10: (0. 05～0. 10), the temperature of 60～80℃ for 6～10 h, the yields of mono-cyanoethyl substituted anilines were 87 %～90 % , and capillary gas chromatographic determination method was used for the contents analysis of N-β-cyanoethyl-o-substituted anilines or N-β-cyanoethyl-p-substituted anilines amongmono-cyanoethylation reactions. All of products were characterized by DTA-TG, UV-Vis, FTIR,~1H NMR, andelemental analyses.