CAJ | 학술논문

目的了解新疆维吾尔族、哈萨克族、汉族成年人颈动脉斑块情况,提高对动脉粥样硬化的预防.方法 2007年10月至2010年3月应用四阶段整群随机抽样法,抽取新疆维吾尔族、哈萨克族、汉族35岁以上人群13 896名.进行问卷、体检和血糖、血脂检测及颈动脉斑块超声检测.采用Logistic回归分析该人群颈动脉斑块形成的主要危险因素.结果颈动脉斑块总检出率为10.2%.经标准化后维吾尔族、哈萨克族、汉族检出率分别为2.31%、1.84%、2.46%.Logistic回归分析显示,年龄(OR 1.032,95%CI 1.026～1.037)、吸烟(OR 1.358,95%CI 1.164～1.585)、总胆固醇(OR 1.075,95%CI 1.018～1.135)、血糖(OR 1.050,95%CI 1.020～1.081)、收缩压(OR 1.011,95%CI 1.008～1.014)是颈动脉斑块形成的独立危险因素,女性(OR 0.653,95%CI 0.545～0.738)、高密度脂蛋白(OR 0.864,95%CI 0.751～0.994)是其保护因素.结论新疆维吾尔族、哈萨克族、汉族颈动脉斑块检出随年龄增长呈增多趋势,且不同民族间存在差异.性别、年龄、吸烟、高密度脂蛋白、总胆固醇、血糖、收缩压均可影响颈动脉斑块的形成,不同性别影响因素不同.
목적 료해신강유오이족、합살극족、한족성년인경동맥반괴정황,제고대동맥죽양경화적예방.방법 2007년10월지2010년3월응용사계단정군수궤추양법,추취신강유오이족、합살극족、한족35세이상인군13 896명.진행문권、체검화혈당、혈지검측급경동맥반괴초성검측.채용Logistic회귀분석해인군경동맥반괴형성적주요위험인소.결과 경동맥반괴총검출솔위10.2%.경표준화후유오이족、합살극족、한족검출솔분별위2.31%、1.84%、2.46%.Logistic회귀분석현시,년령(OR 1.032,95%CI 1.026～1.037)、흡연(OR 1.358,95%CI 1.164～1.585)、총담고순(OR 1.075,95%CI 1.018～1.135)、혈당(OR 1.050,95%CI 1.020～1.081)、수축압(OR 1.011,95%CI 1.008～1.014)시경동맥반괴형성적독립위험인소,녀성(OR 0.653,95%CI 0.545～0.738)、고밀도지단백(OR 0.864,95%CI 0.751～0.994)시기보호인소.결론 신강유오이족、합살극족、한족경동맥반괴검출수년령증장정증다추세,차불동민족간존재차이.성별、년령、흡연、고밀도지단백、총담고순、혈당、수축압균가영향경동맥반괴적형성,불동성별영향인소불동.
Objective To investigate the detection rate of carotid artery plaque in Han, Uygur and Kazakh adult populations of Xinjiang. Methods During the period of October 2007 to March 2010, the present study was performed in 13896 Han, Uygur and Kazakh adults of Xinjiang aged 35 years old and over by a four-stage random sampling method. All subjects were investigated by a standardized questionnaire,physical, biochemical examination and ultrasonography of carotid arteries. Risk factors were analyzed by a logistic regression model. Results The prevalence of carotid artery plaque was 10.2% . After standardization, the detection rate of Chinese Han, Uygur and Kazakh populations was 2.46%, 2. 31% and 1.84% respectively. By the analysis of multivariate logistic regression, age( OR 1.032, 95% CI 1.026-1. 037), smoking( OR 1. 358, 95% CI 1. 164 - 1. 585 ), total cholesterol ( OR 1. 075, 95% CI 1. 018 -1. 135), blood glucose( OR 1. 050, 95% CI 1. 020 - 1. 081 ) and systolic blood pressure( OR 1.011,95% CI 1. 008 - 1. 014 ) were independent risk factors in the occurrence of carotid artery plaque. Females ( OR 0. 653, 95% CI 0. 545 -0. 738 ) and high-density lipoprotein (OR 0. 864, 95% CI 0. 751 -0. 994 )were the protective factors in the occurrence of carotid artery plaque. Conclusion The detection of carotid artery plaque in Xinjiang increases substantially with age and difference exists between nationalities. The associated risk factors of the formation of carotid artery plaque include gender, age, smoking, high-density lipoprotein,total cholesterol, blood glucose and systolic blood pressure. The effect of these factors is different between genders.