中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2010年
4期
270-273,255
,共5页
卵泡刺激素%人%促黄体激素%骨密度
卵泡刺激素%人%促黃體激素%骨密度
란포자격소%인%촉황체격소%골밀도
Follicle stimulating hormone%Human%Luteinizing hormone%Bone density
目的 调查女性年龄相关的血清促卵泡刺激素 (FSH) 和促黄体生成素 (LH) 水平及其与骨密度的关系.方法 测定699例受试者血清FSH和LH浓度及正位腰椎(AP)、侧位腰椎(LP)、总髋部(T-hip)、远端前臂(DF)骨密度,评价血清FSH和LH与年龄、骨密度的关系.结果 FSH和LH从40岁起随增龄而增加,至≥60岁随增龄而下降.绝经前血清FSH和LH的几何平均值(SD)分别为3.94±2.08 IU/L和7.51±2.58 IU/L,绝经后分别为28.8±1.88IU/L和25.6±1.95 IU/L.血清FSH与LH呈高度正相关(r=0.734,P=0.000).FSH和LH与各部位骨密度呈显著负相关,FSH与骨密度的相关程度(r=-0.597～-0.492)好于LH与骨密度(r=-0.332～-0.452)的相关程度.其中FSH(r=-0.597)和LH(r=-0.452)与腰椎骨密度的负相关性最好.结论 成年女性血清FSH和LH随年龄和绝经状态而变化,FSH和LH与骨密度明显相关.血清FSH和LH增加的妇女骨密度下降.
目的 調查女性年齡相關的血清促卵泡刺激素 (FSH) 和促黃體生成素 (LH) 水平及其與骨密度的關繫.方法 測定699例受試者血清FSH和LH濃度及正位腰椎(AP)、側位腰椎(LP)、總髖部(T-hip)、遠耑前臂(DF)骨密度,評價血清FSH和LH與年齡、骨密度的關繫.結果 FSH和LH從40歲起隨增齡而增加,至≥60歲隨增齡而下降.絕經前血清FSH和LH的幾何平均值(SD)分彆為3.94±2.08 IU/L和7.51±2.58 IU/L,絕經後分彆為28.8±1.88IU/L和25.6±1.95 IU/L.血清FSH與LH呈高度正相關(r=0.734,P=0.000).FSH和LH與各部位骨密度呈顯著負相關,FSH與骨密度的相關程度(r=-0.597～-0.492)好于LH與骨密度(r=-0.332～-0.452)的相關程度.其中FSH(r=-0.597)和LH(r=-0.452)與腰椎骨密度的負相關性最好.結論 成年女性血清FSH和LH隨年齡和絕經狀態而變化,FSH和LH與骨密度明顯相關.血清FSH和LH增加的婦女骨密度下降.
목적 조사녀성년령상관적혈청촉란포자격소 (FSH) 화촉황체생성소 (LH) 수평급기여골밀도적관계.방법 측정699례수시자혈청FSH화LH농도급정위요추(AP)、측위요추(LP)、총관부(T-hip)、원단전비(DF)골밀도,평개혈청FSH화LH여년령、골밀도적관계.결과 FSH화LH종40세기수증령이증가,지≥60세수증령이하강.절경전혈청FSH화LH적궤하평균치(SD)분별위3.94±2.08 IU/L화7.51±2.58 IU/L,절경후분별위28.8±1.88IU/L화25.6±1.95 IU/L.혈청FSH여LH정고도정상관(r=0.734,P=0.000).FSH화LH여각부위골밀도정현저부상관,FSH여골밀도적상관정도(r=-0.597～-0.492)호우LH여골밀도(r=-0.332～-0.452)적상관정도.기중FSH(r=-0.597)화LH(r=-0.452)여요추골밀도적부상관성최호.결론 성년녀성혈청FSH화LH수년령화절경상태이변화,FSH화LH여골밀도명현상관.혈청FSH화LH증가적부녀골밀도하강.
Objective Relation among the density of serum FSH and LH that the aim was to investigate Chinese women's age is relevant with BMD.Methods Study of 699 women,Serum FSH and LH concentrations,and BMD were measured at the posteroanterior (PA) spine,lateral spine,total hip and distal forearm.Have appraised serum FSH and LH concentrations and BMD.Results FSH and LH increase,increase age at the same time from 40 years old probably,increase,but drop to 60 years old age at the same time.Serum FSH and geometirc average (SD) of LH before menopause.It is respectively 3.94(2.08)IU/L and 7.51(2.58)IU/L,after men opauseis respectively 28.8(1.88)IU/L and 5.6(1.95)IU/L.Serum FSH and LH present high positive correlation (r=0.734,P=0.000) BMD of SH、LH and different skeleton position presents and shoulders notably relevantly,the relevant intensity of FSH and BMD (r=-0.597～-0.492) always better than LH and BMD (r=-0.332～-0.452),FSH among them (r=-0.597) with LH (r=-0.452) one that is with PA lumbar vertebrae BMD is defeated.Conclusion These data suggest that the circulation concentrations of FSH and LH may vary with Chinese women's age and menopause and may be relevant with BMD.Chinese women's BMD decrease as their serum FSH and LH increase.
