中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2008年
4期
446-448
,共3页
马忠宇%杨敬源%王铜%刘红%冯红旗%裴俊瑞%徐柏楠%刘越%张改改%郭予丹
馬忠宇%楊敬源%王銅%劉紅%馮紅旂%裴俊瑞%徐柏楠%劉越%張改改%郭予丹
마충우%양경원%왕동%류홍%풍홍기%배준서%서백남%류월%장개개%곽여단
克山病%治疗%结果评价%超声心动图
剋山病%治療%結果評價%超聲心動圖
극산병%치료%결과평개%초성심동도
Keshan disease%Therapy%Outcome assessment%Echocardiography
目的 应用超声心动图观察克山病患者自我治疗前后心脏结构及功能的变化,评价克山病患者自我治疗的疗效.方法 在自我治疗前及治疗3、6个月时对31例克山病患者进行超声心动图检查.观察左房内径(LAd)、左室舒张末期内径(LVEDd)、室间隔舒张末期厚度(IVSTd)、左室后壁舒张末期厚度(LVPWTd)、左室质量(LVM)、左室质量指数(LVMI)、左室射血分数(LVEF)和二尖瓣舒张早、晚期血流速度峰比值(E/A).结果 治疗3个月时患者LAd[(35.8±5.1)mm]及LVPWTd[(9.3±1.0)mm]较治疗前[(37.0±5.0)、(9.9±1.2)mm]明显降低(P<0.05);治疗6个月时患者LAd[(34.5±5.0)mm]、IVSTd[(9.5±1.3)mm]、LVEDd[(50.2±7.7)mm]、LVPWTd[(8.7±1.1)mm、LVM[(196.1±87.2)g]和LVMI[(126.5±56.4)g/m2]与治疗前[(37.0±5.0)、(10.2±1.5)、(51.3±8.1)、(9.9±1.2)mm、(230.4±95.5)g、(144.0±54.6)g/m2]和治疗3个月时[(35.8±5.1)、(10.2±1.4)、(51.1±8.1)、(9.3±1.0)mm、(219.4±82.5)g、(136.8±50.0)g/m2]比较均明显降低(P<0.05);E/A及LVEF值在治疗3个月时[1.0±0.5、(59.4±13.3)%]较治疗前[0.9±0.5、(58.1±15.6)%]有所增高,在治疗6个月时[1.0±0.4、(60.7±13.6)%]进一步增高,两两比较差异均无统计学意义(P0.05).结论 克山病患者经过自我治疗后,左室重构受到限制,并发生了逆转,心功能得到了相应改善.超声心动图为克山病患者自我治疗疗效的评价提供了有效的方法.
目的 應用超聲心動圖觀察剋山病患者自我治療前後心髒結構及功能的變化,評價剋山病患者自我治療的療效.方法 在自我治療前及治療3、6箇月時對31例剋山病患者進行超聲心動圖檢查.觀察左房內徑(LAd)、左室舒張末期內徑(LVEDd)、室間隔舒張末期厚度(IVSTd)、左室後壁舒張末期厚度(LVPWTd)、左室質量(LVM)、左室質量指數(LVMI)、左室射血分數(LVEF)和二尖瓣舒張早、晚期血流速度峰比值(E/A).結果 治療3箇月時患者LAd[(35.8±5.1)mm]及LVPWTd[(9.3±1.0)mm]較治療前[(37.0±5.0)、(9.9±1.2)mm]明顯降低(P<0.05);治療6箇月時患者LAd[(34.5±5.0)mm]、IVSTd[(9.5±1.3)mm]、LVEDd[(50.2±7.7)mm]、LVPWTd[(8.7±1.1)mm、LVM[(196.1±87.2)g]和LVMI[(126.5±56.4)g/m2]與治療前[(37.0±5.0)、(10.2±1.5)、(51.3±8.1)、(9.9±1.2)mm、(230.4±95.5)g、(144.0±54.6)g/m2]和治療3箇月時[(35.8±5.1)、(10.2±1.4)、(51.1±8.1)、(9.3±1.0)mm、(219.4±82.5)g、(136.8±50.0)g/m2]比較均明顯降低(P<0.05);E/A及LVEF值在治療3箇月時[1.0±0.5、(59.4±13.3)%]較治療前[0.9±0.5、(58.1±15.6)%]有所增高,在治療6箇月時[1.0±0.4、(60.7±13.6)%]進一步增高,兩兩比較差異均無統計學意義(P0.05).結論 剋山病患者經過自我治療後,左室重構受到限製,併髮生瞭逆轉,心功能得到瞭相應改善.超聲心動圖為剋山病患者自我治療療效的評價提供瞭有效的方法.
목적 응용초성심동도관찰극산병환자자아치료전후심장결구급공능적변화,평개극산병환자자아치료적료효.방법 재자아치료전급치료3、6개월시대31례극산병환자진행초성심동도검사.관찰좌방내경(LAd)、좌실서장말기내경(LVEDd)、실간격서장말기후도(IVSTd)、좌실후벽서장말기후도(LVPWTd)、좌실질량(LVM)、좌실질량지수(LVMI)、좌실사혈분수(LVEF)화이첨판서장조、만기혈류속도봉비치(E/A).결과 치료3개월시환자LAd[(35.8±5.1)mm]급LVPWTd[(9.3±1.0)mm]교치료전[(37.0±5.0)、(9.9±1.2)mm]명현강저(P<0.05);치료6개월시환자LAd[(34.5±5.0)mm]、IVSTd[(9.5±1.3)mm]、LVEDd[(50.2±7.7)mm]、LVPWTd[(8.7±1.1)mm、LVM[(196.1±87.2)g]화LVMI[(126.5±56.4)g/m2]여치료전[(37.0±5.0)、(10.2±1.5)、(51.3±8.1)、(9.9±1.2)mm、(230.4±95.5)g、(144.0±54.6)g/m2]화치료3개월시[(35.8±5.1)、(10.2±1.4)、(51.1±8.1)、(9.3±1.0)mm、(219.4±82.5)g、(136.8±50.0)g/m2]비교균명현강저(P<0.05);E/A급LVEF치재치료3개월시[1.0±0.5、(59.4±13.3)%]교치료전[0.9±0.5、(58.1±15.6)%]유소증고,재치료6개월시[1.0±0.4、(60.7±13.6)%]진일보증고,량량비교차이균무통계학의의(P0.05).결론 극산병환자경과자아치료후,좌실중구수도한제,병발생료역전,심공능득도료상응개선.초성심동도위극산병환자자아치료료효적평개제공료유효적방법.
Objective To observe the change in cardiac shape and heart function and evaluate the effect of self-treatment on patients with Keshan disease by echocardiography. Methods To check the 31 patients with Keshan disease before the self-treatment, and follow them up in the 3rd and 6th months after self-treatment by echocardiography. The left atrium diameter(LAd), left ventricular end-diastolic diameter(LVEDd), the thickness of interventricular septum in end-diastolic(IVSTd), the thickness of LV posterior wall in end-diastolic (LVPWTd), left ventricular mass(LVM), left ventricular mass index(LVMI), left ventricular ejection fraction(LVEF) and mitral valve flow E/A ratio(E/A) were measured. Results The LAd[(35.8±5.1)ram] and LVPWTd[(9.3±1.0)mm] obviously decreased in the 3rd month after serf-treatment compared with prior self-treatment [ (37.0±5.0), (9.9± 1.2)mm](P<0.05). The LAd[(34.5±5.0)mini, IVSTd[(9.5±1.3)mm], LVEDd[(50.2±7.7)mm], LVPWTd [(8.7±1.1)mm], LVM[(196.1±87.2)g] and LVMl[(126.5±56.4)g/m2] obviously decreased in the 6th month after self-treatment compared with prior self-treatment [(37.0±5.0), (10.2±1.5), (51.3±8.1), (9.9±1.2)mm, (230.4±95.5)g, (144.0±54.6)g/m2] and in the 3rd month after self-treatment [(35.8±5.1)mm, (10.2±1.4) ram, (51.1±8.1)nun, (9.3±1.0)mm, (219.4±82.5)g, (136.8±50.0)g/m2] (P<0.05). The results of the mitral valve flow E/A ratio and LVEF in the 3nt month after self-treatment [1.0±0.5, (59.4±13.3)%] were increased compared with the prior self-treatment[0.9±0.5, (58.1±15.6)%], and the results in the 6th month after self-treat- ment[ 1.0±0.4, (60.7±13.6)%] were further inereased compared with before, but there was no signifieant differ- ence(P0.05). Conclusions Self-treatment of Keshan disease patients can improve the heart function by pre- venting left ventrieular remodeling and reversing. Echocardiography can be used as an essential technique to evalu- ate the effect of self-treatment on Keshan disease patients.
