中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2010年
6期
498-502
,共5页
李世岩%黄品同%徐海珊%许立龙%吕江红%寿金朵%赵博文
李世巖%黃品同%徐海珊%許立龍%呂江紅%壽金朵%趙博文
리세암%황품동%서해산%허립룡%려강홍%수금타%조박문
超声检查%微气泡%胃肿瘤%淋巴结转移
超聲檢查%微氣泡%胃腫瘤%淋巴結轉移
초성검사%미기포%위종류%림파결전이
Ultrasonography%Microbubbles%Stomach neoplasms%Lymphatic metastasis
目的 探讨超声双重造影技术在评价胃癌淋巴结转移中的应用价值.方法 经手术病理证实的116例胃癌患者,术前行超声双重造影检查,并对胃癌组织进行超声定量分析,检测基础强度(BI)、峰值强度(PI)、开始增强时间(AT)和达峰时间(TTP)等参数,计算增强强度(EI,EI=PI-BI)和灌注时间(WIT,WIT=TTP-AT).术后根据病理结果将所有患者分为两组:N1组,淋巴结转移组,69例;N0组,无淋巴结转移组,47例.超声双重造影定量分析结果与手术病理结果对比,并采用Kappa法对该方法的可靠性进行检验.结果 N1组胃癌组织BI值显著低于N0组[(1.41±1.56)dB对(3.92±2.82)dB,t=-4.81,P=0.000],EI值显著高于N0组[(20.67±3.71)dB对(14.12±3.75)dB,t=7.31,P=0.000],而WIT值显著短于N0组[(9.12±2.99)s对(10.88±3.05)s,t=-2.43,P=0.018].绘制ROC曲线,通过计算曲线下面积得知,以胃癌组织EI＞17.05 dB作为胃癌淋巴结转移的诊断标准,其灵敏度为80.50%,特异度为76.70%,且具有较高的重复可靠性(Kappa=0.88).结论 胃癌组织EI值可间接评价胃癌的淋巴结转移情况.
目的 探討超聲雙重造影技術在評價胃癌淋巴結轉移中的應用價值.方法 經手術病理證實的116例胃癌患者,術前行超聲雙重造影檢查,併對胃癌組織進行超聲定量分析,檢測基礎彊度(BI)、峰值彊度(PI)、開始增彊時間(AT)和達峰時間(TTP)等參數,計算增彊彊度(EI,EI=PI-BI)和灌註時間(WIT,WIT=TTP-AT).術後根據病理結果將所有患者分為兩組:N1組,淋巴結轉移組,69例;N0組,無淋巴結轉移組,47例.超聲雙重造影定量分析結果與手術病理結果對比,併採用Kappa法對該方法的可靠性進行檢驗.結果 N1組胃癌組織BI值顯著低于N0組[(1.41±1.56)dB對(3.92±2.82)dB,t=-4.81,P=0.000],EI值顯著高于N0組[(20.67±3.71)dB對(14.12±3.75)dB,t=7.31,P=0.000],而WIT值顯著短于N0組[(9.12±2.99)s對(10.88±3.05)s,t=-2.43,P=0.018].繪製ROC麯線,通過計算麯線下麵積得知,以胃癌組織EI＞17.05 dB作為胃癌淋巴結轉移的診斷標準,其靈敏度為80.50%,特異度為76.70%,且具有較高的重複可靠性(Kappa=0.88).結論 胃癌組織EI值可間接評價胃癌的淋巴結轉移情況.
목적 탐토초성쌍중조영기술재평개위암림파결전이중적응용개치.방법 경수술병리증실적116례위암환자,술전행초성쌍중조영검사,병대위암조직진행초성정량분석,검측기출강도(BI)、봉치강도(PI)、개시증강시간(AT)화체봉시간(TTP)등삼수,계산증강강도(EI,EI=PI-BI)화관주시간(WIT,WIT=TTP-AT).술후근거병리결과장소유환자분위량조:N1조,림파결전이조,69례;N0조,무림파결전이조,47례.초성쌍중조영정량분석결과여수술병리결과대비,병채용Kappa법대해방법적가고성진행검험.결과 N1조위암조직BI치현저저우N0조[(1.41±1.56)dB대(3.92±2.82)dB,t=-4.81,P=0.000],EI치현저고우N0조[(20.67±3.71)dB대(14.12±3.75)dB,t=7.31,P=0.000],이WIT치현저단우N0조[(9.12±2.99)s대(10.88±3.05)s,t=-2.43,P=0.018].회제ROC곡선,통과계산곡선하면적득지,이위암조직EI＞17.05 dB작위위암림파결전이적진단표준,기령민도위80.50%,특이도위76.70%,차구유교고적중복가고성(Kappa=0.88).결론 위암조직EI치가간접평개위암적림파결전이정황.
Objective To investigate the clinical value of double contrast-enhanced ultrasonography (DCUS) in diagnosing lymph nodes metastasis of gastric carcinoma.Methods One hundred and sixteen patients with gastric cancer diagnosed by gastroscope and confirmed by pathology after operation were examined by DCUS preoperatively.The enhanced characteristic of gastric carcinoma tissues was assessed by autotracking contrast quantification(ACQ) software.The baseline intensity(BI), peak intensity(PI), arrival time(AT) and time to peak(TTP) of gastric cancer was measured automatically,and the enhanced intensity (EI) and wash-in time(WIT) of gastric cancer was calculated manually (EI=PI-BI; WIT=TTP-AT).All of the subjects were divided into two groups according to their lymph nodes status postoperatively:group N1,sixty-nine patients with lymph nodes metastasis; and group N0, forty-seven patients without lymph nodes metastasis.The DCUS quantitative analysis and pathological results of these two groups were compared each other.The Kappa's test was used for inter-rater reliability.Results BI of group N1 in the gastric carcinoma tissues was lower than that of group N0 significantly [(1.41 ± 1.56)dB vs (3.92 ± 2.82)dB, t = - 4.81, P = 0.000].EI of group N1 in the gastric carcinoma tissues was higher than that of group N0 significantly [(20.67±3.71)dB vs (14.12±3.75)dB, t=7.31, P=0.000].Moreover, there was a significant difference of WIT in the gastric carcinoma tissues between these two groups[(9.12±2.99)s vs (10.88±3.05)s, t =-2.43, P=0.018].The WIT in patients with lymph nodes metastasis was shorter than that without it. A cut-off value ＞17.05 dB of EI in gastric cancer tissues for assessing the lymph nodes metastasis had a sensitivity of 80.50% and specificity of 76.70% respectively obtained by the area under the ROC curve. The Kappa value of this method was 0.88.Conclusions EI of gastric cancer tissues can be considered as a new potential index to evaluate the lymph nodes metastasis of gastric cancer.
