中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2012年
17期
1187-1189
,共3页
李晓冬%阎雪%陈丽华%唐红娟%沈鸿敏%周英杰
李曉鼕%閻雪%陳麗華%唐紅娟%瀋鴻敏%週英傑
리효동%염설%진려화%당홍연%침홍민%주영걸
腔内超声%正常女童%特发性性早熟
腔內超聲%正常女童%特髮性性早熟
강내초성%정상녀동%특발성성조숙
Intraluminal ultrasound%Idiopathic precocious puberty%Normal girls
目的 探讨腔内超声在正常女童和特发性性早熟( ICPP)女童性发育状态诊断及治疗中的应用价值.方法 2008年10月至2010年2月就诊于河北医科大学第二医院妇科内分泌门诊和儿科生长发育门诊的女童,采用腔内超声测量180名正常女童和44例ICPP女童子宫长、宽、厚,宫颈长度,卵巢容积,最大卵泡直径.并对其中17例ICPP女童应用促性腺激素释放激素类似物(GnRHa)治疗前后各超声值变化进行对比.结果 正常女童平均在9岁后子宫、卵巢体积明显增长,9岁组子宫体积( 1.87 ±0.58)ml,7岁组(1.03±0.24)ml;卵巢体积(3.01±2.73)ml,7岁组(0.98±0.36) ml;ICPP女童各超声测量值均大于正常女童;ICPP女童治疗后较治疗前各超声测量值明显降低.子宫体积治疗前(1.16±0.19) ml,治疗后(1.02±0.15)ml;卵巢体积治疗前(2.11±0.48) ml,治疗后(1.72±0.55) ml;最大卵泡直径治疗前(1.36±0.25)cm,治疗后(1.16±0.36)cm.结论 腔内超声能够作为评估青春期性发育状态以及性早熟诊断及治疗效果评估的辅助手段.
目的 探討腔內超聲在正常女童和特髮性性早熟( ICPP)女童性髮育狀態診斷及治療中的應用價值.方法 2008年10月至2010年2月就診于河北醫科大學第二醫院婦科內分泌門診和兒科生長髮育門診的女童,採用腔內超聲測量180名正常女童和44例ICPP女童子宮長、寬、厚,宮頸長度,卵巢容積,最大卵泡直徑.併對其中17例ICPP女童應用促性腺激素釋放激素類似物(GnRHa)治療前後各超聲值變化進行對比.結果 正常女童平均在9歲後子宮、卵巢體積明顯增長,9歲組子宮體積( 1.87 ±0.58)ml,7歲組(1.03±0.24)ml;卵巢體積(3.01±2.73)ml,7歲組(0.98±0.36) ml;ICPP女童各超聲測量值均大于正常女童;ICPP女童治療後較治療前各超聲測量值明顯降低.子宮體積治療前(1.16±0.19) ml,治療後(1.02±0.15)ml;卵巢體積治療前(2.11±0.48) ml,治療後(1.72±0.55) ml;最大卵泡直徑治療前(1.36±0.25)cm,治療後(1.16±0.36)cm.結論 腔內超聲能夠作為評估青春期性髮育狀態以及性早熟診斷及治療效果評估的輔助手段.
목적 탐토강내초성재정상녀동화특발성성조숙( ICPP)녀동성발육상태진단급치료중적응용개치.방법 2008년10월지2010년2월취진우하북의과대학제이의원부과내분비문진화인과생장발육문진적녀동,채용강내초성측량180명정상녀동화44례ICPP녀동자궁장、관、후,궁경장도,란소용적,최대란포직경.병대기중17례ICPP녀동응용촉성선격소석방격소유사물(GnRHa)치료전후각초성치변화진행대비.결과 정상녀동평균재9세후자궁、란소체적명현증장,9세조자궁체적( 1.87 ±0.58)ml,7세조(1.03±0.24)ml;란소체적(3.01±2.73)ml,7세조(0.98±0.36) ml;ICPP녀동각초성측량치균대우정상녀동;ICPP녀동치료후교치료전각초성측량치명현강저.자궁체적치료전(1.16±0.19) ml,치료후(1.02±0.15)ml;란소체적치료전(2.11±0.48) ml,치료후(1.72±0.55) ml;최대란포직경치료전(1.36±0.25)cm,치료후(1.16±0.36)cm.결론 강내초성능구작위평고청춘기성발육상태이급성조숙진단급치료효과평고적보조수단.
Objective To assess the significance of intraluminal ultrasound in the diagnosis of developmental status and treatment effect in normal and idiopathic precocious puberty (ICPP) girls.Methods Endorectal ultrasonography was used to measure the parameters of uterine length,width,thickness,cervix length,ovarian volume and maximum follicular length in normal girls and compare their differences between pre- and post-treatment by gonadotropin-releasing hormone analogues (GnRHa) in idiopathic precocious puberty girls.Results The ultrasonic parameters of uterus and ovary in normal girls significantly increased in average 9-year-old girls( 1.87 ±0.58) ml of uterine volume in 9-year-old group vs (1.03 ±0.24) ml in 7-year-old group; ovarian volume( 3.01 ±2.73) ml of uterine volume in 9-year-old group vs 0.98 ± 0.36 ml in 7-year-old group. They were much greater in ICPP girls and decreased significantly at post-treatment,( 1.16 ± 0.19 )ml of uterus volume pre-treatment vs ( 1.02 ± 0.15 )ml post-treatment; (2.11 ± 0.48) ml of ovarian volume pre-treatment,( 1.72 ± 0.55 ) ml post-treatment; ( 1.36 ± 0.25)cm of the biggest follicular diameter pre-treatment,(1.16 ± 0.36) cm post-treatment.Conclusion Endosonography is an important tool of evaluating the development status and treatment effect in normal and ICPP girls.