国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2011年
8期
966-969
,共4页
伐昔洛韦%带状疱疹%窄谱UVB%后遗神经痛
伐昔洛韋%帶狀皰疹%窄譜UVB%後遺神經痛
벌석락위%대상포진%착보UVB%후유신경통
Valacyclovir%Herpes zoster%Narrow-band UVB%Postherpetic neuralgia(PHN)
目的 观察窄谱UVB联合伐昔洛韦治疗带状疱疹的临床疗效.方法 对比分析窄谱UVB联合伐昔洛韦组与对照组患者的总体疗效、止疱时间、结痂时间、脱痂时间及VAS得分等.结果 窄谱UVB联合伐昔洛韦组有效治疗率为80.6%,显著高于对照组60.3%的有效治疗率,差异具有显著性(Z=3.410,P=0.003);窄谱UVB联合伐昔洛韦组止疱时间为(3.39±0.97)天、结痂时间为(6.54±1.18)天、脱痂时间为(11.18±3.78)天及总病程为(10.56±2.14)天均显著少于对照组;两组间胃肠道反应(A组11.3%、B组14.3%)、嗜睡(A组6.5%、B组9.5%)等不良反应发生情况比较差异均无显著性差异(x2=0.035,P=0.852;x2=0.401,P=0.527).结论 窄谱UVB联合伐昔洛韦能够有效提高带状疱疹的治疗效果,临床应用安全可靠.
目的 觀察窄譜UVB聯閤伐昔洛韋治療帶狀皰疹的臨床療效.方法 對比分析窄譜UVB聯閤伐昔洛韋組與對照組患者的總體療效、止皰時間、結痂時間、脫痂時間及VAS得分等.結果 窄譜UVB聯閤伐昔洛韋組有效治療率為80.6%,顯著高于對照組60.3%的有效治療率,差異具有顯著性(Z=3.410,P=0.003);窄譜UVB聯閤伐昔洛韋組止皰時間為(3.39±0.97)天、結痂時間為(6.54±1.18)天、脫痂時間為(11.18±3.78)天及總病程為(10.56±2.14)天均顯著少于對照組;兩組間胃腸道反應(A組11.3%、B組14.3%)、嗜睡(A組6.5%、B組9.5%)等不良反應髮生情況比較差異均無顯著性差異(x2=0.035,P=0.852;x2=0.401,P=0.527).結論 窄譜UVB聯閤伐昔洛韋能夠有效提高帶狀皰疹的治療效果,臨床應用安全可靠.
목적 관찰착보UVB연합벌석락위치료대상포진적림상료효.방법 대비분석착보UVB연합벌석락위조여대조조환자적총체료효、지포시간、결가시간、탈가시간급VAS득분등.결과 착보UVB연합벌석락위조유효치료솔위80.6%,현저고우대조조60.3%적유효치료솔,차이구유현저성(Z=3.410,P=0.003);착보UVB연합벌석락위조지포시간위(3.39±0.97)천、결가시간위(6.54±1.18)천、탈가시간위(11.18±3.78)천급총병정위(10.56±2.14)천균현저소우대조조;량조간위장도반응(A조11.3%、B조14.3%)、기수(A조6.5%、B조9.5%)등불량반응발생정황비교차이균무현저성차이(x2=0.035,P=0.852;x2=0.401,P=0.527).결론 착보UVB연합벌석락위능구유효제고대상포진적치료효과,림상응용안전가고.
Objective To investigate and compare the effect of narrow-band UVB combined with valacyclovir hydrochloride in treatment to Herpes Zoster. Methods Comparisons of general effect,blain scrab and visual analogue scale score between the patients of narrow-band UVB combined with valacyclovir hydrochloride group and the control group. Results The general effect of the narrow-band UVB combined with valacyclovir hydrochloride group was 80.6%, which was significantly higher than that of the control group(Z=3.410, P=0.003). The narrow-band UVB combined with valacyclovir hydrochloride group took shorter time in easing pain and blain scrab while there was no significant differences of the adverse reaction between the two groups (x2=0.035, P=0.852; x 2=0.401, P=0.527). Conclusion Narrow-band UVB combined with valacyclovir hydrochloride was effective and safe for the treatment of Herpes Zoster.
