国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2009年
3期
142-145
,共4页
慢性阻塞性肺疾病%生命质量%影响因素
慢性阻塞性肺疾病%生命質量%影響因素
만성조새성폐질병%생명질량%영향인소
Chronic obstructive pulmonary disease%Quality of life%Influening factors
目的 对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者生命质量及其相关因素进行分析.方法 选择山西医科大学第一医院呼吸内科门诊及住院稳定期慢性阻塞性肺疾病患者126例.选用由蔡映云教授等设计的慢性阻塞性肺疾病生命质量测量表对患者进行评估.据COPD患者人口学特征、流行病学特征和临床诊治经验对可能影响患者生命质量并有可能进行干预的11项因素进行调查和分析,包括年龄、职业、营养状况、受教育程度、经济状况、吸烟量、呼吸困难程度、急性加重频率、体育锻炼、共患疾病、第1秒用力呼气容积占预计值的百分比和动脉血氧分压.结果 纳入COPD患者126例,所填问卷均完整、准确,全部进入结果 分析.①动脉血氧分压对生命质量总分及日常生活能力有影响,其标准回归系数β分别为-0.192、和-0.205,t分别为-3.202和-2.791,P值均＜0.01.②呼吸困难程度对生命质量总分和日常生活能力、焦虑心理症状和抑郁心理症状3个因子均有影响,标准回归系数β分别为0.204、0.265、0.264和0.366,t分别为2.841、3.487、2.982和4.582,P值均＜0.01.③肺功能对日常生活能力和社会活动状况两个因子有影响,其标准回归系数β分别为0.173和0.205,t分别为2.013和2.503,P值均＜0.01.结论 影响COPD患者生命质量的主要因素有年龄、体质量指数、体育锻炼、共患疾病、急性加重次数、呼吸困难程度、肺功能和动脉血氧分压.根据标准回归系数的大小可以看出,各因子对生命质量总分的影响从大到小依次为体育锻炼、急性加重次数、呼吸困难程度、动脉血氧分压、共患疾病、体质量指数和年龄.
目的 對慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者生命質量及其相關因素進行分析.方法 選擇山西醫科大學第一醫院呼吸內科門診及住院穩定期慢性阻塞性肺疾病患者126例.選用由蔡映雲教授等設計的慢性阻塞性肺疾病生命質量測量錶對患者進行評估.據COPD患者人口學特徵、流行病學特徵和臨床診治經驗對可能影響患者生命質量併有可能進行榦預的11項因素進行調查和分析,包括年齡、職業、營養狀況、受教育程度、經濟狀況、吸煙量、呼吸睏難程度、急性加重頻率、體育鍛煉、共患疾病、第1秒用力呼氣容積佔預計值的百分比和動脈血氧分壓.結果 納入COPD患者126例,所填問捲均完整、準確,全部進入結果 分析.①動脈血氧分壓對生命質量總分及日常生活能力有影響,其標準迴歸繫數β分彆為-0.192、和-0.205,t分彆為-3.202和-2.791,P值均＜0.01.②呼吸睏難程度對生命質量總分和日常生活能力、焦慮心理癥狀和抑鬱心理癥狀3箇因子均有影響,標準迴歸繫數β分彆為0.204、0.265、0.264和0.366,t分彆為2.841、3.487、2.982和4.582,P值均＜0.01.③肺功能對日常生活能力和社會活動狀況兩箇因子有影響,其標準迴歸繫數β分彆為0.173和0.205,t分彆為2.013和2.503,P值均＜0.01.結論 影響COPD患者生命質量的主要因素有年齡、體質量指數、體育鍛煉、共患疾病、急性加重次數、呼吸睏難程度、肺功能和動脈血氧分壓.根據標準迴歸繫數的大小可以看齣,各因子對生命質量總分的影響從大到小依次為體育鍛煉、急性加重次數、呼吸睏難程度、動脈血氧分壓、共患疾病、體質量指數和年齡.
목적 대만성조새성폐질병(chronic obstructive pulmonary disease,COPD)환자생명질량급기상관인소진행분석.방법 선택산서의과대학제일의원호흡내과문진급주원은정기만성조새성폐질병환자126례.선용유채영운교수등설계적만성조새성폐질병생명질량측량표대환자진행평고.거COPD환자인구학특정、류행병학특정화림상진치경험대가능영향환자생명질량병유가능진행간예적11항인소진행조사화분석,포괄년령、직업、영양상황、수교육정도、경제상황、흡연량、호흡곤난정도、급성가중빈솔、체육단련、공환질병、제1초용력호기용적점예계치적백분비화동맥혈양분압.결과 납입COPD환자126례,소전문권균완정、준학,전부진입결과 분석.①동맥혈양분압대생명질량총분급일상생활능력유영향,기표준회귀계수β분별위-0.192、화-0.205,t분별위-3.202화-2.791,P치균＜0.01.②호흡곤난정도대생명질량총분화일상생활능력、초필심리증상화억욱심리증상3개인자균유영향,표준회귀계수β분별위0.204、0.265、0.264화0.366,t분별위2.841、3.487、2.982화4.582,P치균＜0.01.③폐공능대일상생활능력화사회활동상황량개인자유영향,기표준회귀계수β분별위0.173화0.205,t분별위2.013화2.503,P치균＜0.01.결론 영향COPD환자생명질량적주요인소유년령、체질량지수、체육단련、공환질병、급성가중차수、호흡곤난정도、폐공능화동맥혈양분압.근거표준회귀계수적대소가이간출,각인자대생명질량총분적영향종대도소의차위체육단련、급성가중차수、호흡곤난정도、동맥혈양분압、공환질병、체질량지수화년령.
Objective To study the major factors which could affect the quality of life in patients with chronic obstructive pulmonary disease(COPD).Methods One hundred and twenty-six inpatients or outpatients with stable COPD were selected from the Department of Respiratory Medicine.the first Hospital of Shanm Medical University between August 2006 and November 2007.The quality of life of the patients were measured with COPD questionaire designed by professer CAI Yin-yun in shanxi.Based on the d&nographie characteristics investigation,epidemiologic feature and clinical experience of diagnose and therapia of the patients with COPD,11 factors,which may be interfered in,were investigated and analysed including age,employment,economic status,nutritional status,smoking condition,dyspnea degree,the frequency of acute exacerbation,physical exercise,comorbidity,forced expiratory volume in first second(FEV1)and partial pressure of oxygen of artery(Pa02).Results All the questionnaires filled by the 126 patients were accurate and complete,and all were involved to the analysis of results.①Partial pressure of oxygen of artery affected the total scores and activity of daily living(standard regression coefficient p was-0.192 and-0.205,t=-3.202 and-2.791,all P＜0.01.②Dyspnea degree affected the total scores and 3 dimensions including activity of daily living,anxious psychological symptom and depressed psyehology symptom (standard regression coefficient 8 was 0.204,0.265,0.264,and 0.366,t=2.841,3.487,2.982 and 4.582,all P＜0.01).③Lung function affected activity of daily living and social activities condition (standard regression coefficient β was 0.173 and 0.205,t=2.013 and 2.503,all P＜0.01).Condusiom The major factors which affect the quality of life of stable COPD patients are age,BMI,physical exercise,comorbidity,the frequency of acute exacerbation,dyspnea degree,pulmonary ventilation function and PaO2.According to standard rgression coefficient β,we can learn about that the nlain factors that influence total scores are physical exercise,the frequency of acute exacerbation,dyspnea degree,PaO2,comorbidity,BMI and age.
