CAJ | 학술논문

目的评价比较内、外科两种方法治疗高血压脑出血的疗效.方法对所有已发表的脑出血随机对照试验(RCT)进行Meta分析.结果 (1)共纳入13个符合要求的RCT研究,包括脑出血患者2 842例.(2) Meta分析结果显示脑出血内、外科治疗患者死亡率OR合并值在发病后1个月为0.73 (0.48,1.13),两组差异无统计学意义(P＞0.05).但在发病3- 12个月后OR合并值为0.77(0.64,0.91),外科治疗组明显优于内科治疗组,差异有统计学意义(P＜0.05).(3)发病3个月以后,患者生活依赖的OR合并值为0.84(0.39,1.81),两组差异无统计学意义(P＞0.05),但在发病6-12个月后,外科治疗组患者生活能力明显优于保守治疗组,OR值为0.63(0.41,0.98),差异有统计学意义.结论外科手术远期疗效优于内科保守治疗,能显著提高脑出血患者存活率,并有效改善日常生活能力.
목적 평개비교내、외과량충방법치료고혈압뇌출혈적료효.방법 대소유이발표적뇌출혈수궤대조시험(RCT)진행Meta분석.결과 (1)공납입13개부합요구적RCT연구,포괄뇌출혈환자2 842례.(2) Meta분석결과현시뇌출혈내、외과치료환자사망솔OR합병치재발병후1개월위0.73 (0.48,1.13),량조차이무통계학의의(P＞0.05).단재발병3- 12개월후OR합병치위0.77(0.64,0.91),외과치료조명현우우내과치료조,차이유통계학의의(P＜0.05).(3)발병3개월이후,환자생활의뢰적OR합병치위0.84(0.39,1.81),량조차이무통계학의의(P＞0.05),단재발병6-12개월후,외과치료조환자생활능력명현우우보수치료조,OR치위0.63(0.41,0.98),차이유통계학의의.결론 외과수술원기료효우우내과보수치료,능현저제고뇌출혈환자존활솔,병유효개선일상생활능력.
Objective To evaluate the efficacy between surgical treatment and conservative treatment in intracerebral hemorrhage by meta analysis.Method We identified randomized controlled trials (RCT) of intracerebral hemorrhage.And Meta - analysis was conducted on homogeneous studies.Result Thirteen RCTs (2 842 patients) were included.M eta- analysis was conducted on included studies including surgical treatment or medical treatment for intracerebral hemorrhage patients.The mortality OR (95％ CI) values was 0.73 (0.48,1.13 ) at the end of 1 month.There was no significant difference of survival rate between two groups ( surgical treatment group and conservative treatment group,P ＞ 0.05 ).But at the end of 3 - 12 months,the mortality OR ( 95％ CI) values was 0.77 (0.64,0.91 ).The difference between two groups was not significant ( P ＜0.05).The patients dependence OR(95％ CI) value was 0.84 (0.39,1.81 ) at the end of 3 month.The difference between two groups was not significant( P ＞0.05).But at the end of 6 - 12 months,patients dependence OR ( 95％ CI ) value was 0.63 ( 0.41,0.98 ).The difference of two groups was significant ( P ＜ 0.05 ).Conclusions As compared with conservative treatment,surgical treatment could remarkably decrease long- term mortality,and improve the ability of daily life.