中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2009年
6期
639-640
,共2页
复发性翼状胬肉%角膜缘干细胞%羊膜%移植术
複髮性翼狀胬肉%角膜緣榦細胞%羊膜%移植術
복발성익상노육%각막연간세포%양막%이식술
Recurrent pterygium%Limbal stem cells%Amniotic membrane%Transplantation
目的 比较角膜缘干细胞移植术和羊膜移植术治疗复发性翼状胬肉的临床疗效.方法 将66例(69只眼)患者随机分为两组,分别采用角膜缘干细胞移植术(33例34只眼)和羊膜移植术(33例35只眼)治疗,术后随访1～2年.结果 角膜缘干细胞移植组1只眼复发,复发率为2.94%;羊膜移植组8只眼复发,复发率为22.9%,两组比较差异有统计学意义(χ2=4.389,P<0.05).角膜创面上皮平均愈合时间角膜缘干细胞移植为3～5(4.5±2.4)d,羊膜移植组为5±8(6.5±2.6)d,两组比较差异有统计学意义,(t=3.317,P<0.05).结论 角膜缘干细胞移植术治疗复发性翼状胬肉复发率低,角膜创面修复快,是一种理想的手术方法,值得推广应用.
目的 比較角膜緣榦細胞移植術和羊膜移植術治療複髮性翼狀胬肉的臨床療效.方法 將66例(69隻眼)患者隨機分為兩組,分彆採用角膜緣榦細胞移植術(33例34隻眼)和羊膜移植術(33例35隻眼)治療,術後隨訪1～2年.結果 角膜緣榦細胞移植組1隻眼複髮,複髮率為2.94%;羊膜移植組8隻眼複髮,複髮率為22.9%,兩組比較差異有統計學意義(χ2=4.389,P<0.05).角膜創麵上皮平均愈閤時間角膜緣榦細胞移植為3～5(4.5±2.4)d,羊膜移植組為5±8(6.5±2.6)d,兩組比較差異有統計學意義,(t=3.317,P<0.05).結論 角膜緣榦細胞移植術治療複髮性翼狀胬肉複髮率低,角膜創麵脩複快,是一種理想的手術方法,值得推廣應用.
목적 비교각막연간세포이식술화양막이식술치료복발성익상노육적림상료효.방법 장66례(69지안)환자수궤분위량조,분별채용각막연간세포이식술(33례34지안)화양막이식술(33례35지안)치료,술후수방1～2년.결과 각막연간세포이식조1지안복발,복발솔위2.94%;양막이식조8지안복발,복발솔위22.9%,량조비교차이유통계학의의(χ2=4.389,P<0.05).각막창면상피평균유합시간각막연간세포이식위3～5(4.5±2.4)d,양막이식조위5±8(6.5±2.6)d,량조비교차이유통계학의의,(t=3.317,P<0.05).결론 각막연간세포이식술치료복발성익상노육복발솔저,각막창면수복쾌,시일충이상적수술방법,치득추엄응용.
Objective To compare the therapeutic effects of recurrent pterygium treated by limbai stem cell transplantation and amniotic membrane transplantation. Methods Sixty-six eases (69eyes) with recur-rent pterygium were randomly divided into limbal stem cell autograft transplantation group (33cases, 34eyes) and amniotic membrane transplantation group (33eases, 35eyes). The post operative follow-up periods were 12 to 24 months. Results Recurrence of one eye was noted in limbal stem cell autogratft transplantation group, the recurrent rate was 2.94%, however recurrence of eight eyes were noted in anmiotie membrane transplantation group, the recurrent rate was 22.9%. There was statistical significant difference between two groups (χ2=4.389,P <0.05 ). The average epithelial recovering time of corneal wound was 4.5 days,and 6.5 days,respectively,the difference was statistical significant (t =3.317, P <0.01 ). Conclusion Limbal stem cells autograft transplantation can decrease the recurrent rate, improve epithelial recovering time of corneal wound, it is an ideal method for treating the recurrent pterygium and is worth to spreading.
