中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2008年
12期
713-715
,共3页
骨坏死%骨肉瘤%头颈部肿瘤
骨壞死%骨肉瘤%頭頸部腫瘤
골배사%골육류%두경부종류
Osteonecrosis%Osteosarcoma%Head and neck neoplasms
目的 回顾性分析头颈部放疗诱发颌面部恶性肿瘤的发病状况及表现.方法 临床分析273例曾接受头颈部放疗导致放射性颌骨坏死(osteoradionecrosis,ORN)的患者中,发现6例发生颌骨恶性肿瘤,＜30岁1例,≥30岁4例,≥60岁l例.分析273例ORN发生在放疗后的时间、患者的年龄、性别分布.结果 3个年龄组放疗后诱发颌骨恶性肿瘤的构成比(单纯ORN与诱发颌骨恶性肿瘤之比为276:6)、发病年限(≤5年3例、≤10年1例、＞10年2例)、性别(男女之比为3:3)比较后,差异无统计学意义.结论 放疗诱发颌骨恶性病变多位于上颌,主要表现为上颌窦高分化鳞状细胞癌或上颌骨骨肉瘤.上颌窦癌发生隐蔽,易误诊,而上颌骨骨肉瘤增长迅速.
目的 迴顧性分析頭頸部放療誘髮頜麵部噁性腫瘤的髮病狀況及錶現.方法 臨床分析273例曾接受頭頸部放療導緻放射性頜骨壞死(osteoradionecrosis,ORN)的患者中,髮現6例髮生頜骨噁性腫瘤,＜30歲1例,≥30歲4例,≥60歲l例.分析273例ORN髮生在放療後的時間、患者的年齡、性彆分佈.結果 3箇年齡組放療後誘髮頜骨噁性腫瘤的構成比(單純ORN與誘髮頜骨噁性腫瘤之比為276:6)、髮病年限(≤5年3例、≤10年1例、＞10年2例)、性彆(男女之比為3:3)比較後,差異無統計學意義.結論 放療誘髮頜骨噁性病變多位于上頜,主要錶現為上頜竇高分化鱗狀細胞癌或上頜骨骨肉瘤.上頜竇癌髮生隱蔽,易誤診,而上頜骨骨肉瘤增長迅速.
목적 회고성분석두경부방료유발합면부악성종류적발병상황급표현.방법 림상분석273례증접수두경부방료도치방사성합골배사(osteoradionecrosis,ORN)적환자중,발현6례발생합골악성종류,＜30세1례,≥30세4례,≥60세l례.분석273례ORN발생재방료후적시간、환자적년령、성별분포.결과 3개년령조방료후유발합골악성종류적구성비(단순ORN여유발합골악성종류지비위276:6)、발병년한(≤5년3례、≤10년1례、＞10년2례)、성별(남녀지비위3:3)비교후,차이무통계학의의.결론 방료유발합골악성병변다위우상합,주요표현위상합두고분화린상세포암혹상합골골육류.상합두암발생은폐,역오진,이상합골골육류증장신속.
Objective To investigate the incidence of radiation-induced maxillary malignancy after radiotherapy for head and neck cancer. Methods A total of 273 patients who suffered from osteoradionecrosis after radiotherapy for head and neck cancer were evaluated.Among them,6 patients were presented with carcinoma and sarcoma arising from maxillary area after radiotherapy.Results Radiationinduced maxillary cancers happened at a rate of 2.2% in the patients with osteoradionecrosis.There were no statistically significant difierences in age,sex and the time interval between the radiotherapy and the cancer occurence.Conclusions Radiation-induced malignancy after radiotherapy for head and neck cancer is mainly located in maxilla,presenting as squamous cell carcinoma or sarcoma of the maxillary sinus.
