CAJ | 학술논문

目的探讨重症肌无力(MG)患者抑郁、焦虑、失眠的发生率及其相关因素.方法采用汉密顿焦虑量表、汉密顿抑郁量表、匹兹堡睡眠质量指数量表、MG日常生活量表及自制一般情况调查表对2009年11月至2010年7月在中山大学附属第一医院神经科门诊就诊的161例MG患者进行调查,并用逐步Logistic回归统计方法对各相关因素进行分析.结果本组患者中抑郁发生率58.3%,焦虑发生率45.3%,失眠发生率39.1%.对MG影响较大的相关因素有:并发抑郁是年龄、肢体乏力、日常生活量表评分;并发失眠是年龄、呼吸困难、患胸腺瘤、术后1个月情况、糖皮质激素用量;并发焦虑的相关因素是分享经验.结论 MG患者半数左右存在不同程度的情感障碍,其相关因素可为防治MG并发情感障碍提供参考依据.
목적 탐토중증기무력(MG)환자억욱、초필、실면적발생솔급기상관인소.방법 채용한밀돈초필량표、한밀돈억욱량표、필자보수면질량지수량표、MG일상생활량표급자제일반정황조사표대2009년11월지2010년7월재중산대학부속제일의원신경과문진취진적161례MG환자진행조사,병용축보Logistic회귀통계방법대각상관인소진행분석.결과 본조환자중억욱발생솔58.3%,초필발생솔45.3%,실면발생솔39.1%.대MG영향교대적상관인소유:병발억욱시년령、지체핍력、일상생활량표평분;병발실면시년령、호흡곤난、환흉선류、술후1개월정황、당피질격소용량;병발초필적상관인소시분향경험.결론 MG환자반수좌우존재불동정도적정감장애,기상관인소가위방치MG병발정감장애제공삼고의거.
Objective To investigate the incidence rate and correlation factors of depression,anxiety and insomnia in patients with myasthenia gravis (MG).Methods A total of 161 MG patients were assessed and graded with HAMD,HAMA,PSQI,QMG,ADL and a self-made scale chart.And the correlation factors were analyzed by Logistic stepwise regression.Results The prevalence of depression,anxiety and insomnia was 58.3%,45.3% and 39.1% respectively.The correlation factors with significant influences on MG were as follows: depression with age,physical weakness,score of QMG,life scale grading;anxiety with experience-sharing;insomnia age,dyspnea,thymoma,physical status at 1 month post-operation,prednisone dose and score of QMG.Conclusion Nearly one half of the MG patients suffer from affective disorders to different degrees.And an analysis of its correlation factors provides references to prevent and treat the affective disorders concurrently with MG.