中国生物医学工程学报
中國生物醫學工程學報
중국생물의학공정학보
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2009年
5期
668-673,685
,共7页
陆荣生%易红%倪中华%齐建昌
陸榮生%易紅%倪中華%齊建昌
륙영생%역홍%예중화%제건창
血管中心线%血管直径%细化算法%图像分割
血管中心線%血管直徑%細化算法%圖像分割
혈관중심선%혈관직경%세화산법%도상분할
vascular centerline%vascular diameter%thinning algorithm%image segmentation
血管中心线及直径的测量是血管类疾病诊断和微创介入治疗的重要依据.当前研究主要依据图像细化算法,但是细化算法缺乏计算结果的一致性.提出一种基于弹性小球动态平衡的血管中心线和直径的测量方法.首先在血管内部以交互的方式输入一条多段线(polyline)来确定感兴趣的血管部位,然后对多段线离散化为一组点,通过对离散点逐步膨胀为小球以及在小球与血管壁碰撞的两个力影响下,对小球和多段线同时变形,最后在平衡状态下得到的多段线即是血管中心线,小球直径就是该处血管直径.实验中,通过对模拟血管图像和临床DSA图像的量化测量及与常用方法对比,表明所提出算法能够精确地得到血管中心线与血管直径.
血管中心線及直徑的測量是血管類疾病診斷和微創介入治療的重要依據.噹前研究主要依據圖像細化算法,但是細化算法缺乏計算結果的一緻性.提齣一種基于彈性小毬動態平衡的血管中心線和直徑的測量方法.首先在血管內部以交互的方式輸入一條多段線(polyline)來確定感興趣的血管部位,然後對多段線離散化為一組點,通過對離散點逐步膨脹為小毬以及在小毬與血管壁踫撞的兩箇力影響下,對小毬和多段線同時變形,最後在平衡狀態下得到的多段線即是血管中心線,小毬直徑就是該處血管直徑.實驗中,通過對模擬血管圖像和臨床DSA圖像的量化測量及與常用方法對比,錶明所提齣算法能夠精確地得到血管中心線與血管直徑.
혈관중심선급직경적측량시혈관류질병진단화미창개입치료적중요의거.당전연구주요의거도상세화산법,단시세화산법결핍계산결과적일치성.제출일충기우탄성소구동태평형적혈관중심선화직경적측량방법.수선재혈관내부이교호적방식수입일조다단선(polyline)래학정감흥취적혈관부위,연후대다단선리산화위일조점,통과대리산점축보팽창위소구이급재소구여혈관벽팽당적량개력영향하,대소구화다단선동시변형,최후재평형상태하득도적다단선즉시혈관중심선,소구직경취시해처혈관직경.실험중,통과대모의혈관도상화림상DSA도상적양화측량급여상용방법대비,표명소제출산법능구정학지득도혈관중심선여혈관직경.
Measurement of vascular centerline and diameter is a fundamental step in diagnosing vascular diseases and planning minimally invasive surgery. Current research is mainly based on image thinning techniques, but different thinning algorithms can not guarantee the consistency of different algorithms. This paper presented an original approach using the dynamic balance of bouncing balls to measure the vascular centerline and diameter in angiogram. A polyline was first inputted inside the vascular disease region, and automatically descretized to a set of points attached with initial balls. Then, the center and radius of each ball were deformed under the elastic expending force and the bouncing force from vascular boundary. When every ball reached a stable state, the deformed polyline and ball diameters represented the vascular centerline and local diameters, respectively. The proposed method was tested using simulated vascular images and raw DSA images and compared with other approaches. The results showed that the method of dynamic balance of bouncing balls was robust and effective in extracting vascular centerline and diameters for medial treatments.