CAJ | 학술논문

目的探讨抗焦虑治疗联合认知行为疗法对初诊高血压患者疗效的影响.方法将60例初诊高血压患者随机分为A组(常规降压治疗+抗焦虑治疗和认知行为疗法)及B组(常规降压治疗),同时选择15例年龄、性别相匹配的健康人为C组.每组各观察8周,比较各组治疗后的降压效果、焦虑自评量表(SAS)评分变化及血浆血管性假性血友病因子(VWF)和血清高敏C-反应蛋白(hs-CRP)水平的变化.结果初诊高血压患者存在明显的焦虑状态.抗焦虑治疗联合认知行为疗法后A组患者血压下降更明显,SAS评分平均减少显著低于B组(P<0.01),血浆VWF及血清hs-CRP水平均较B、C组显著降低(均P<0.01).结论初诊高血压患者存在明显的焦虑状态.抗焦虑治疗联合认知行为疗法较常规降压治疗明显提高初诊高血压患者的降压效果,同时也明显地降低焦虑情绪及血浆VWF及血清hs-CRP水平.
목적 탐토항초필치료연합인지행위요법대초진고혈압환자료효적영향.방법 장60례초진고혈압환자수궤분위A조(상규강압치료+항초필치료화인지행위요법)급B조(상규강압치료),동시선택15례년령、성별상필배적건강인위C조.매조각관찰8주,비교각조치료후적강압효과、초필자평량표(SAS)평분변화급혈장혈관성가성혈우병인자(VWF)화혈청고민C-반응단백(hs-CRP)수평적변화.결과 초진고혈압환자존재명현적초필상태.항초필치료연합인지행위요법후A조환자혈압하강경명현,SAS평분평균감소현저저우B조(P<0.01),혈장VWF급혈청hs-CRP수평균교B、C조현저강저(균P<0.01).결론 초진고혈압환자존재명현적초필상태.항초필치료연합인지행위요법교상규강압치료명현제고초진고혈압환자적강압효과,동시야명현지강저초필정서급혈장VWF급혈청hs-CRP수평.
Objective To evaluate the curative effect of combined cognitive behaviioral therapy with alprazolam anti-anxiety. on patients with preliminary hypertemsion. Methods After evaluating by self-rating anxiety scale (SAS) ,60 outpatients with preliminary hypertension were randomly divided into A and B groups. The A group (n = 29) were accepted the combined cognitive behavioral therapy with alprazolam anti-anxiety for 8 weeks at the basis with medication, the B group ( n = 31 ) given rontine medication only. Meantimes, fifteen healthy volunteers who matched with age and sex were selected as the normal control group ( C group ). The blood pressure of all the subjects were recorded at the begin and after eight-weeks therapy,and the levels of plasma von willebrand factor (VWF) and serum high-sensitive reaction protein(hs-CRP) were measured respectively. The evaluating by self-rating anxiety scale (SAS) were performed in the A and B groups,before and after the treatment at the same time. Results The patients with preliminary hypertension have higher SAS score as well as the levels of plasma VWF and serum hs-CRP. After psychotherapy,in A group,the SAS score,the levels of VWF and serum hs-CRP, and the blood pressure were significantly decreased( P < 0. 01 ),compared with those in B group, however, were still significantly higher than those of C group( P < 0. 01 ). Conclusion The patients with preliminary hypertension showed some-degrees anxious emotion. By combined cognitive behavioral therapy with alprazolam anti-anxiety,we could not only more positively control the patients, blood pressure,but also improve the patients emotion states,as well as decrease the levels of VWF and hs-CRP.