CAJ | 학술논문

目的研究剧烈横向摆动对休克犬麻醉后海水浸泡的血流动力学影响.方法选择健康犬14只平均分为对照组和浸泡组,每组7只.在基础麻醉、气管插管后监测心率(HR)、有创平均主动脉压(MAP)、中心静脉压(CVP)、肺动脉压(MPAP)后.静脉放血制成失血性休克犬模型.对照组麻醉后在横向大于45°,频率10～15次/min剧烈摇摆20 min;浸泡组放入温度20℃左右的海水中浸泡30min后,再与对照组同样麻醉后剧烈摇摆20 min,记录2次摇摆前、摇摆1、2、4、6、10、15、20 min时的血流动力学变化情况.结果两次摆动均引起血流动力学的明显向下波动,但都在5～10min左右恢复至摇摆前水平;对照组摆动引起的血压下降程度、持续时间略高于浸泡组(P<0.05).结论在剧烈的左右摆动中,休克犬是否遭受海水浸泡会对麻醉后的血流动力学变化有不同程度的影响.
목적 연구극렬횡향파동대휴극견마취후해수침포적혈류동역학영향.방법 선택건강견14지평균분위대조조화침포조,매조7지.재기출마취、기관삽관후감측심솔(HR)、유창평균주동맥압(MAP)、중심정맥압(CVP)、폐동맥압(MPAP)후.정맥방혈제성실혈성휴극견모형.대조조마취후재횡향대우45°,빈솔10～15차/min극렬요파20 min;침포조방입온도20℃좌우적해수중침포30min후,재여대조조동양마취후극렬요파20 min,기록2차요파전、요파1、2、4、6、10、15、20 min시적혈류동역학변화정황.결과 량차파동균인기혈류동역학적명현향하파동,단도재5～10min좌우회복지요파전수평;대조조파동인기적혈압하강정도、지속시간략고우침포조(P<0.05).결론 재극렬적좌우파동중,휴극견시부조수해수침포회대마취후적혈류동역학변화유불동정도적영향.
Objective To investigate hemodynamic effects of simulated violent rolling of naval vessels on lesion induced by seawater immersion combined with shock in anesthetized dogs. Methods Fourteen dogs were randomly divided into two groups: the immersion group and the control group, each consisting of 7 animals. In the immersion group, the animals were immersed in the seawater for 30 minutes, then taken out of the seawater. Heart rate (HR), central venous pressure (CVP), mean pulmonary arterial pressure (MPAP) were carefully monitored, following basal anesthesia and endotracheal intubation. Then, a model of hemorrhagic shock was developed by venetomy. Animals in the control group experienced violent roiling with a horizontal angle greater than 45 degrees and frequencies of 10～15 times per minute for a duration 20 minutes. The experimental group was immersed in the seawater with a temperature of about 20 ℃ and for a duration 30 minutes, then also experienced identical violent rolling as the control group for 20 minutes. Hemodynamic changes were recorded both before rolling and 1, 2, 4, 6, 10, 15, 20 minutes after rolling. Results Downward fluctuation of hemodynamic data could be induced by rollings, but returned to pro - rolling levels in 5～10 minutes. For animals in the control group, the extent of drop in blood pressure was higher when a comparison was made between the control and the immersion groups (P<0.05). Conclusions Violent rolling had certain effects on hemodynamic changes in anesthetized dogs combined with seawater immersion following anesthesia.