中华骨科杂志
中華骨科雜誌
중화골과잡지
CHINESE JOURNAL OF ORTHOPAEDICS
2008年
8期
678-683
,共6页
郑召民%邝冠明%董智勇%吕维加%李朝阳%吕游%陈辉%刘辉%张奎渤%李佛保
鄭召民%鄺冠明%董智勇%呂維加%李朝暘%呂遊%陳輝%劉輝%張奎渤%李彿保
정소민%광관명%동지용%려유가%리조양%려유%진휘%류휘%장규발%리불보
脊柱骨折%骨质疏松%甲基丙烯酸甲酯类%生物力学
脊柱骨摺%骨質疏鬆%甲基丙烯痠甲酯類%生物力學
척주골절%골질소송%갑기병희산갑지류%생물역학
Spinal fractures%Osteopomsis%Methylmethacrylates%Biomechanics
目的 探讨新型Vessel-X骨材料填充器对注射聚甲基丙烯酸甲酯(PMMA)在椎体内分布影响及对椎体力学性能的修复效果.方法 将新鲜冰冻人椎体标本14个随机分单侧穿刺和双侧穿刺组.每组7椎.测量各标本的骨密度、前后缘和中线高度以及原始刚度和强度后,建立压缩骨折模型.测量骨折后标本的高度和剐度.应用Vessel-X骨材料填充器注射PMMA后再次测量椎体的高度、强度和刚度.观察填充器在椎体内的膨胀情况及PMMA在椎体内的分布情况.结果 两组椎体术后的强度均较原始大,但术后强度比较差异无统计学意义.两组椎体术后刚度较骨折后水平均有恢复,双侧组较单侧组刚度恢复效果好.术后椎体各部位的高度均增加,但未恢复到原始高度水平.术后两组椎体中线两侧的高度差比较差异无统计学意义.轴位透视下见骨水泥在椎体内呈椭圆形或长椭圆形分布,与填充器在体外膨胀后的形状相似.横断标本后,见填充器能在椎体内良好膨胀,包裹绝大部分PMMA,仅少量PMMA渗漏到网层外,但均局限在网层周围.结论 Vessel-X骨材料填充器在椎体标本内能包裹绝大部分PMMA,可防止骨水泥渗漏,且能恢复骨折椎体的力学性能和高度.
目的 探討新型Vessel-X骨材料填充器對註射聚甲基丙烯痠甲酯(PMMA)在椎體內分佈影響及對椎體力學性能的脩複效果.方法 將新鮮冰凍人椎體標本14箇隨機分單側穿刺和雙側穿刺組.每組7椎.測量各標本的骨密度、前後緣和中線高度以及原始剛度和彊度後,建立壓縮骨摺模型.測量骨摺後標本的高度和剮度.應用Vessel-X骨材料填充器註射PMMA後再次測量椎體的高度、彊度和剛度.觀察填充器在椎體內的膨脹情況及PMMA在椎體內的分佈情況.結果 兩組椎體術後的彊度均較原始大,但術後彊度比較差異無統計學意義.兩組椎體術後剛度較骨摺後水平均有恢複,雙側組較單側組剛度恢複效果好.術後椎體各部位的高度均增加,但未恢複到原始高度水平.術後兩組椎體中線兩側的高度差比較差異無統計學意義.軸位透視下見骨水泥在椎體內呈橢圓形或長橢圓形分佈,與填充器在體外膨脹後的形狀相似.橫斷標本後,見填充器能在椎體內良好膨脹,包裹絕大部分PMMA,僅少量PMMA滲漏到網層外,但均跼限在網層週圍.結論 Vessel-X骨材料填充器在椎體標本內能包裹絕大部分PMMA,可防止骨水泥滲漏,且能恢複骨摺椎體的力學性能和高度.
목적 탐토신형Vessel-X골재료전충기대주사취갑기병희산갑지(PMMA)재추체내분포영향급대추체역학성능적수복효과.방법 장신선빙동인추체표본14개수궤분단측천자화쌍측천자조.매조7추.측량각표본적골밀도、전후연화중선고도이급원시강도화강도후,건립압축골절모형.측량골절후표본적고도화과도.응용Vessel-X골재료전충기주사PMMA후재차측량추체적고도、강도화강도.관찰전충기재추체내적팽창정황급PMMA재추체내적분포정황.결과 량조추체술후적강도균교원시대,단술후강도비교차이무통계학의의.량조추체술후강도교골절후수평균유회복,쌍측조교단측조강도회복효과호.술후추체각부위적고도균증가,단미회복도원시고도수평.술후량조추체중선량측적고도차비교차이무통계학의의.축위투시하견골수니재추체내정타원형혹장타원형분포,여전충기재체외팽창후적형상상사.횡단표본후,견전충기능재추체내량호팽창,포과절대부분PMMA,부소량PMMA삼루도망층외,단균국한재망층주위.결론 Vessel-X골재료전충기재추체표본내능포과절대부분PMMA,가방지골수니삼루,차능회복골절추체적역학성능화고도.
Objective To find out the effect of Vessel-X bone void filling container on polymethyl methacrylate(PMMA)distilbution controlling within the vertebral body and the restoration of biomechanical properties after augmentation.Metbods 14 fresh frozen human vertebrae specimens were randomly divided into two groups according to unipedicular and bipedicular injection.After measuring the bone mineral density (BMD) and vertebral height,each vertebrae were applied to axle lead by MTS machine to test the initial strength and stiffness,and subsequently created simultaneous compressive fracture models.After the augmentation procedure,the biomechanical properties and the vertebral height were similarly measured as preoperation.The expansion of Vessel-X bone void filling container and the PMMA distribution within the vertebral body were morphologically observed by crossing the specimen in sagittal midline,and also integraded with radiography results.Results The strength of specimen was significantly increased after augmentation procedure but without significant difference between groups.The stiffness was also significantly restored compared with that of fractured level and the bipedicular group had better restoration results than the unipedicular groups.The height restoration wag found in both groups but no difference between two sides of midline pre-and post-operation.In axial view of radiography.the distribution of cement in the vertebral body Wag just like the configuration of ellipse which wag similar to the shape Vessel-X bone void falling container expanded in vitro.After crossed.the Vessel-X bone void filling container expanded well in the vertebral body and the container enwrapped most of the PMMA iniected.No PMMA Wag found out of the vertebral body.Conclusion This novel Vessel-X bone void filling container system can enwrap most of the PMMA injected into the vertebral body,reduce cement leakage,and restore biomechanical properties and height of simultaneous vertebral compressive fracture.
